EFSA toxicology reference values

Hexa-2,4-dien-1-ol

SOURCE efsa openfoodtox 3 0 export repository

Hexa-2,4-dien-1-ol (CAS 111-28-4). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.

Hexa-2,4-dien-1-ol is a cannabis analyte contaminant represented in the cannabis public dataset.

CAS 111-28-4 Cannabis Analyte

Substance Identity

Analyte identity and classification used for this cannabis substance page.

SOURCE efsa substances
Analyte name
Hexa-2,4-dien-1-ol
CAS number
111-28-4
Contaminant class
Cannabis Analyte

Contaminant Class Badge

Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.

SOURCE State Cannabis Regulations
Cannabis Analyte Cannabis contaminant class used to group state testing rows.

Dataset Snapshot

Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.

SOURCE cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
111-28-4

EFSA Substance Identity

EFSA substance identity rows matched by chemical name or CAS.

SOURCE efsa openfoodtox 3 0 export repository
Hexa-2,4-dien-1-ol
CAS 111-28-4 / mono-constituent substance
C6H10O / 4 dossier(s)

EFSA Reference Values

Reference values from efsa_reference_values_v2 for toxicology and food-safety context.

SOURCE efsa openfoodtox 3 0 export repository
DescriptorValuePopulationEndpointBody
TTC Cramer Class I 30 µg/kg bw/day consumers - -
TTC Cramer Class I 30 µg/kg bw/day consumers - -
TTC Cramer Class I 30 µg/kg bw/day consumers - -
margin of safety - consumers - -

EFSA Study Results

Endpoint-level study rows from efsa_study_results matched to this substance.

SOURCE efsa openfoodtox 3 0 export repository
EndpointSpeciesRouteEffectAssessment
boiling point - - - experimental study
appearance / physical state / colour - - - experimental study
solubility in organic solvents / fat solubility - - - experimental study
melting point/freezing point - - - experimental study
other: - - - experimental study
refractive index - - - experimental study
water solubility - - - experimental study
Carcinogenicity_EU_PPP - - - Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000.
Carcinogenicity_EU_PPP - - - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of flavouring substances from subgroup 1.1.4 of FGE.19 in the Flavouring Group Evaluation 203 Revision 2 (FGE.203Rev2). In FGE. 203 Revision 1, the Panel concluded that the genotoxic potential could not be ruled out for the flavouring substances in this FGE.
Carcinogenicity_EU_PPP - - - The EFSA Panel on Food Additives and Flavourings was requested to evaluate 29 flavouring substances attributed to the Flavouring Group Evaluation 70 (FGE.70), using the Procedure in Commission Regulation (EC) No 1565/2000.
Carcinogenicity_EU_PPP - - - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 203 (FGE.203) concerns 17 substances. The 17 substances correspond to subgroup 1.1.4 of FGE.19. Twelve of these substances are alpha,beta-unsaturated aldehydes with two or more conjugated double bonds with and without additional non-conjugated double bonds [FL-no: 05.057, 05.064, 05.071, 05.084, 05.101, 05.108, 05.125, 05.127, 05.140, 05.141, 05.173 and 05.196] and five are precursors for such aldehydes [FL-no: 02.139, 02.153, 02.162, 02.188 and 09.573]. Based on the available data on carcinogenicity and genotoxicity there is a safety concern for hexa-2(trans),4(trans)-dienal [FL-no: 05.057] since a non-threshold mechanism cannot be excluded. This conclusion also applies to the other substances of this FGE. Therefore, the substances of this FGE cannot be evaluated through the Procedure. The Panel requests data which clarify whether the carcinogenic effects were based on a thresholded mechanism.
Genetic Toxicity - - - Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000.

Frequently Asked Questions

FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.

SOURCE page FAQ dataset

What is the regulatory limit for Hexa-2,4-dien-1-ol in cannabis?

Hexa-2,4-dien-1-ol does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.

Which states test for Hexa-2,4-dien-1-ol?

Hexa-2,4-dien-1-ol does not have state-level cannabis testing rows in the fetched page data.

What are the EFSA reference values for Hexa-2,4-dien-1-ol?

Hexa-2,4-dien-1-ol has 4 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class I, margin of safety.

Is Hexa-2,4-dien-1-ol also regulated in cosmetics or food?

Hexa-2,4-dien-1-ol has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.