EFSA toxicology reference values
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde
SOURCE
efsa openfoodtox 3 0 export repository
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde (CAS 116-26-7). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 116-26-7
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde
CAS number
116-26-7
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
116-26-7
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde
CAS 116-26-7 / mono-constituent substance
C10H14O / 4 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| margin of safety | ca.200,000 other: | consumers | 322f56e1-2494-4567-b7ac-17dd69319ed7 | - |
| margin of safety | ca.200,000 other: | consumers | d01c7b4f-86ad-4e7f-8436-6af37e13bd16 | - |
| margin of safety | ca.200,000 other: | consumers | d01c7b4f-86ad-4e7f-8436-6af37e13bd16 | - |
| margin of safety | >2,000,000 other: | consumers | 3ae9e92f-918d-42d2-8d75-291b17b9b237 | - |
| margin of safety | >2,000,000 other: | consumers | d6df051d-3702-4742-bdb4-bc39dcd54cdc | - |
| margin of safety | >2,000,000 other: | consumers | 3ae9e92f-918d-42d2-8d75-291b17b9b237 | - |
| critical study not identified | - | consumers | - | other: |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| sub-chronic toxicity: other route | rat | - | 10 mg/kg bw/day | - |
| sub-chronic toxicity: other route | rat | - | 10 mg/kg bw/day | - |
| sub-chronic toxicity: other route | rat | - | 10 mg/kg bw/day | - |
| sub-chronic toxicity: other route | rat | - | 10 mg/kg bw/day | - |
| sub-chronic toxicity: oral | rat | oral: gavage | 120 other: | - |
| sub-chronic toxicity: oral | rat | oral: gavage | 120 other: | - |
| sub-chronic toxicity: other route | dog | - | 120 other: | - |
| sub-chronic toxicity: other route | dog | - | 120 other: | - |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. The revision is made due to consideration of one additional substance, 2,6,6-trimethylcyclohexa-1,3-diene-1-carbaldehyde [FL-no: 05.104], compared to the previous version of FGE.73. This substance has been evaluated in FGE.209 due to structural concern for genotoxicity, and has been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 16 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of nine primary saturated or unsaturated alicyclic alcohol, aldehyde and esters evaluated in the Flavouring Group Evaluation 12, Revision 2 (FGE.12Rev2). |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. This revision is made due to consideration of one additional substance, beta-ionyl acetate [FL-no: 09.305], compared to the previous version of FGE.73 (FGE.73Rev2). This substance has been evaluated in FGE.213Rev1 due to structural concern for genotoxicity, and has been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 18 alicyclic alcohols, aldehydes, acids and related esters and one phenethyl alcohol evaluated by the JECFA (59th and 63rd meeting). |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. In the previous version of Flavouring Group Evaluation 73 (FGE.73), EFSA considered 16 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA at their 59th meeting. This revision is made due to consideration of two additional substances, santalyl acetate [FL-no: 09.034] and santalyl phenylacetate [FL-no: 09.712], compared to the previous version of FGE.73 (FGE.73Rev1). These substances have been evaluated in FGE.207 due to structural concern for genotoxicity, and have been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 18 alicyclic primary alcohols, aldehydes, acids and related esters and one phenethyl alcohol evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of 10 primary saturated or unsaturated alicyclic alcohols, aldehydes and esters evaluated in the Flavouring Group Evaluation 12, Revision 3 (FGE.12Rev3). |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present Flavouring Group Evaluation 209 (FGE.209), corresponding to subgroup 2.3 of FGE.19, concerns one cyclic aldehyde with the alpha,beta-unsaturation in conjugation with the ring system. The alpha,beta-unsaturated aldehyde and ketone structures are considered alerts for genotoxicity and the data on genotoxicity previously available did not rule out the concern for genotoxicity. Accordingly, the Panel has requested additional genotoxicity data for this substance, 2,6,6-trimethylcyclohexa-1,3-diene-1-carbaldehyde [FL-no: 05.104], according to the test strategy. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
page FAQ dataset
What is the regulatory limit for 2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde in cannabis?
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde?
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde?
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde has 11 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class I, margin of safety, critical study not identified.
Is 2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde also regulated in cosmetics or food?
2,6,6-Trimethylcyclohexa-1,3-diene-1-carbaldehyde has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.