EFSA toxicology reference values
S-2-Butyl 3-methylbutanethioate
S-2-Butyl 3-methylbutanethioate (CAS 2432-91-9). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
S-2-Butyl 3-methylbutanethioate is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
Contaminant Class Badge
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Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| margin of safety | 170,000 other: | consumers | 2824638a-2d91-479d-8ae0-beda664ef83b | - |
| margin of safety | 170,000 other: | consumers | 2824638a-2d91-479d-8ae0-beda664ef83b | - |
| margin of safety | 170,000 other: | consumers | 2824638a-2d91-479d-8ae0-beda664ef83b | - |
| margin of safety | 170,000 other: | consumers | d3d98485-d880-4617-b46f-9f7adfbacdf2 | - |
| margin of safety | 170,000 other: | consumers | ac0db5e4-1f67-4875-875f-e0fd1bfd9b23 | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| sub-chronic toxicity: oral | rat | oral: feed | 6.63 other: | - |
| sub-chronic toxicity: oral | rat | oral: feed | 6.63 other: | - |
| sub-chronic toxicity: oral | rat | oral: feed | 6.63 other: | - |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 80 flavouring substances in the Flavouring Group Evaluation 8, Revision 5 (FGE.08Rev5), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 80 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. Compared to FGE.08Rev4, this FGE.08Rev5 includes toxicity data for one supporting substance 2,5-dihydroxy-2,5-dimethyl-1,4-dithiane [FL-no: 15.006], which support the evaluation of the candidate substance 2,5-dihydroxy-1,4-dithiane [FL-no: 15.134]. Furthermore, a 90-day study on the candidate substance spiro(2,4-dithia-1-methyl-8-oxabicyclo[3.3.0]octane-3,3'-(1'-oxa-2'-methyl)-cyclopentane) and spiro(2,4-dithia-6-methyl-7-oxabicyclo[3.3.0]octane-3,3'-(1'-oxa-2'-methyl)-cyclopentane) [FLno: 15.007] has been reconsidered after submission of an explanatory note from EFFA. |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 70 flavouring substances in the Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 70 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation (FGE) deals with 70 straight or branched chain or heterogeneous ring aliphatic hydrocarbons containing one or more sulphur atoms. The sulphurcontaining functional groups are present as thiols, sulphides or sulphones. Based on their structures, the candidate substances can be subdivided into 11 subgroups. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel is asked to evaluate 52 flavouring substances in the Flavouring Group Evaluation 8 (FGE.08), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 52 flavouring substances belong to chemical groups 20, Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation deals with 52 aliphatic and alicyclic mono-and dithiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 of Annex I of Regulation (EC) No 1565/2000. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 66 flavouring substances in the Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 66 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation (FGE) deals with 66 straight or branched chain or heterogeneous ring aliphatic hydrocarbons containing one or more sulphur atoms. The sulphur-containing functional groups are present as thiols, sulphides or sulphones. Based on their structures, the candidate substances can be subdivided into 10 subgroups. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 67 flavouring substances in the Flavouring Group Evaluation 8, Revision 2 (FGE.08Rev2), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 67 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation (FGE) deals with 67 straight or branched chain or heterogeneous ring aliphatic hydrocarbons containing one or more sulphur atoms. The sulphurcontaining functional groups are present as thiols, sulphides or sulphones. Based on their structures, the candidate substances can be subdivided into 10 subgroups. |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 80 flavouring substances in the Flavouring Group Evaluation 8, Revision 4 (FGE.08Rev4), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 80 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The FGE.08Rev4 includes the assessment of 10 additional candidate substances [FL-no: 12.299, 12.300, 12.300, 12.301, 12.302, 12.303, 12.304, 12.305, 12.306, 16.062 and 16.122] compared to FGE.08Rev3. Therefore, the present FGE.08Rev4 deals with 80 flavouring substances in total. These are divided into 11 subgroups. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 67 flavouring substances in the Flavouring Group Evaluation 8, Revision 2 (FGE.08Rev2), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 67 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation (FGE) deals with 67 straight or branched chain or heterogeneous ring aliphatic hydrocarbons containing one or more sulphur atoms. The sulphurcontaining functional groups are present as thiols, sulphides or sulphones. Based on their structures, the candidate substances can be subdivided into 10 subgroups. |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 80 flavouring substances in the Flavouring Group Evaluation 8, Revision 5 (FGE.08Rev5), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 80 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. Compared to FGE.08Rev4, this FGE.08Rev5 includes toxicity data for one supporting substance 2,5-dihydroxy-2,5-dimethyl-1,4-dithiane [FL-no: 15.006], which support the evaluation of the candidate substance 2,5-dihydroxy-1,4-dithiane [FL-no: 15.134]. Furthermore, a 90-day study on the candidate substance spiro(2,4-dithia-1-methyl-8-oxabicyclo[3.3.0]octane-3,3'-(1'-oxa-2'-methyl)-cyclopentane) and spiro(2,4-dithia-6-methyl-7-oxabicyclo[3.3.0]octane-3,3'-(1'-oxa-2'-methyl)-cyclopentane) [FLno: 15.007] has been reconsidered after submission of an explanatory note from EFFA. |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 70 flavouring substances in the Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 70 flavouring substances belong to chemical groups 20 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation (FGE) deals with 70 straight or branched chain or heterogeneous ring aliphatic hydrocarbons containing one or more sulphur atoms. The sulphurcontaining functional groups are present as thiols, sulphides or sulphones. Based on their structures, the candidate substances can be subdivided into 11 subgroups. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for S-2-Butyl 3-methylbutanethioate in cannabis?
S-2-Butyl 3-methylbutanethioate does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for S-2-Butyl 3-methylbutanethioate?
S-2-Butyl 3-methylbutanethioate does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for S-2-Butyl 3-methylbutanethioate?
S-2-Butyl 3-methylbutanethioate has 11 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class I, margin of safety.
Is S-2-Butyl 3-methylbutanethioate also regulated in cosmetics or food?
S-2-Butyl 3-methylbutanethioate has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.