NOAEL Data REACH Registered Cosmetic Ingredient

Cinnamyl butyrate

Also known as: Butanoic acid, 3-phenyl-2-propenyl ester, Butanoic acid, 3-​phenyl-​2-​propen-​1-​yl ester, Butyric acid, cinnamyl este, Cinnamyl alcohol, butyrate, 3-Phenylprop-2-enyl butanoate (+14 more)

CAS 103-61-7

Cinnamyl butyrate (CAS 103-61-7) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for CINNAMYL BUTYRATE →

SOURCE noael studies public
NOAEL studies
10
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 25 fields
Name
Cinnamyl butyrate
CAS Number
103-61-7
DTXSID
DTXSID2059277
Molecular Formula
C13H16O2
InChI Key
YZYPQKZWNXANRB-UHFFFAOYSA-N
Monoisotopic Mass
204.11503
Synonyms
Butanoic acid, 3-phenyl-2-propenyl esterButanoic acid, 3-​phenyl-​2-​propen-​1-​yl esterButyric acid, cinnamyl esteCinnamyl alcohol, butyrate3-Phenylprop-2-enyl butanoateEC No.: 203-128-7BRN 3200585Butynoic acid, 3-phenyl-2-propenyl esterCinnamyl butanoateCinnamyl n-butyrateEINECS 203-128-7FEMA No. 2296

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 10 of 10 studies
ValueUnitEndpointRouteSpeciesSource
TKZ9V37P1GUNIIFDA UNII substance identifier--openFDA substances
TKZ9V37P1GUNIIFDA UNII substance identifier--openFDA substances
TKZ9V37P1GUNIIFDA UNII substance identifier--openFDA substances
TKZ9V37P1GUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
2700ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
=275mg/kg bw/dayNOAELoralRatToxValDB_EFSA
=275mg/kg bw/dayNOAELoral: feedRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
=275mg/kg bw/dayNOAELoral: feedRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 10 of 10 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredCinnamyl butyrate203-128-7ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Cinnamyl butyrate?

Cinnamyl butyrate has 10 NOAEL studies in the database. The lowest reported value is TKZ9V37P1G UNII. Source: openFDA substances.

What regulatory lists include Cinnamyl butyrate?

Cinnamyl butyrate appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Cinnamyl butyrate used in cosmetics?

Yes, Cinnamyl butyrate is also indexed as a cosmetic ingredient under the name CINNAMYL BUTYRATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Cinnamyl butyrate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Cinnamyl butyrate used outside industrial chemicals?

Cinnamyl butyrate also appears in cosmetics, food safety, cannabis databases.