What is the NOAEL for Geranyl formate?
Geranyl formate has 11 NOAEL studies in the database. The lowest reported value is 72O586X6ZI UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Geranyl formate
Also known as: (2E)-3,7-Dimethylocta-2,6-dien-1-yl formate, 2,6-Octadien-1-ol, 3,7-dimethyl-, 1-formate, (2E)-, 2,6-Octadien-1-ol, 3,7-dimethyl-, formate, (2E)-, 2,6-Octadien-1-ol, 3,7-dimethyl-, formate, (E)-, (E)-3,7-Dimethyl-2,6-octadien-1-ol formate (+15 more)
CAS 105-86-2
Geranyl formate (CAS 105-86-2) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Geranyl formate
CAS Number
105-86-2
DTXSID
DTXSID0047614
Molecular Formula
C11H18O2
InChI Key
FQMZVFJYMPNUCT-YRNVUSSQSA-N
Monoisotopic Mass
182.13068
Synonyms
(2E)-3,7-Dimethylocta-2,6-dien-1-yl formate2,6-Octadien-1-ol, 3,7-dimethyl-, 1-formate, (2E)-2,6-Octadien-1-ol, 3,7-dimethyl-, formate, (2E)-2,6-Octadien-1-ol, 3,7-dimethyl-, formate, (E)-(E)-3,7-Dimethyl-2,6-octadien-1-ol formate(E)-3,7-Dimethyl-2,6-octadienyl formatetrans-2,6-Dimethyl-2,6-octadien-8-yl methanoateFORMATE, GERANYL2,6-Octadien-1-ol,3,7-dimethyl-,formate,(E)-4-02-00-00035BRN 1724191trans-3,7-Dimethyl-2,6-octadien-1-ol formate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
9 records
FragranceNo specific technical functionFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 72O586X6ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 72O586X6ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 72O586X6ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 72O586X6ZI | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1296 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >6000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =345 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =345 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =345 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Geranyl formate | 203-339-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3182514
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Geranyl formate?
Geranyl formate appears on 5 regulatory/inventory lists including Australia; Food and drug - smoking-related products, IFRA Transparency, Europe, and 2 more. Source: EPA CPDat.
Is Geranyl formate used in cosmetics?
Yes, Geranyl formate is also indexed as a cosmetic ingredient under the name Geranyl Formate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Geranyl formate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Geranyl formate used outside industrial chemicals?
Geranyl formate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.