NOAEL Data REACH Registered Cosmetic Ingredient

9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)-

CAS 106-16-1

9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- (CAS 106-16-1) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Hydroxyethyl Stearamide-MIPA →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)-
CAS Number
106-16-1
DTXSID
DTXSID40883298
Molecular Formula
C20H39NO3
InChI Key
JYDIHAYTECQGQK-UZRURVBFSA-N
Monoisotopic Mass
341.292994

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Surfactant (surface active agent)Anti-static agentViscosity modifierFoamant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
Q5ZUN5RM0TUNIIFDA UNII substance identifier--openFDA substances
Q5ZUN5RM0TUNIIFDA UNII substance identifier--openFDA substances
Q5ZUN5RM0TUNIIFDA UNII substance identifier--openFDA substances
Q5ZUN5RM0TUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered(R)-12-hydroxy-N-(2-hydroxyethyl)oleamide203-368-2ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3394382
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for 9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)-?

9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- has 4 NOAEL studies in the database. The lowest reported value is Q5ZUN5RM0T UNII. Source: openFDA substances.

Is 9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- used in cosmetics?

Yes, 9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- is also indexed as a cosmetic ingredient under the name Hydroxyethyl Stearamide-MIPA. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does 9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- have different safety status in cosmetics vs industrial chemicals?

9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- is classified GHS Danger (H315, H318) in the chemicals database but is allowed in EU cosmetics.

Is 9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- used outside industrial chemicals?

9-Octadecenamide, 12-hydroxy-N-(2-hydroxyethyl)-, (9Z,12R)- also appears in cosmetics, pharmaceutical databases.