What is the NOAEL for Ethyl dodecanoate?
Ethyl dodecanoate has 8 NOAEL studies in the database. The lowest reported value is 1 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ethyl dodecanoate
Also known as: EINECS 203-386-0, FEMA No. 2441, UNII-F389D4MD5K, Dodecanoic acid,ethyl ester, Ethyl N-dodecanote (+5 more)
CAS 106-33-2
Ethyl dodecanoate (CAS 106-33-2) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Ethyl dodecanoate
CAS Number
106-33-2
DTXSID
DTXSID4047044
Molecular Formula
C14H28O2
InChI Key
MMXKVMNBHPAILY-UHFFFAOYSA-N
Monoisotopic Mass
228.20893
Synonyms
EINECS 203-386-0FEMA No. 2441UNII-F389D4MD5KDodecanoic acid,ethyl esterEthyl N-dodecanoteEthyl ester dodecanoic acidEthyllaurateFEMA 2441Lauric acid, ethyl ester (8CI)lauric acid ethyl ester
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
13 records
Softener and conditionerFragranceNo specific technical functionFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=1 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| F389D4MD5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F389D4MD5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F389D4MD5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F389D4MD5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 7776 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ethyl laurate | 203-386-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187842
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Ethyl dodecanoate?
Ethyl dodecanoate appears on 5 regulatory/inventory lists including Europe, Australia; Food and drug - smoking-related products, IFRA Transparency, and 2 more. Source: EPA CPDat.
Is Ethyl dodecanoate used in cosmetics?
Yes, Ethyl dodecanoate is also indexed as a cosmetic ingredient under the name Ethyl Laurate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethyl dodecanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Ethyl dodecanoate used outside industrial chemicals?
Ethyl dodecanoate also appears in cosmetics, pharmaceutical, cannabis databases.