Warning GHS02GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Propyl propionate

Also known as: 4-02-00-00707, BRN 1699993, EINECS 203-389-7, FEMA No. 2958, NSC 72022 (+11 more)

CAS 106-36-5

Propyl propionate (CAS 106-36-5) is a chemical substance with GHS signal word Warning; key hazard signal: H226; H332. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Propyl Propionate →

SOURCE NOAEL studies
NOAEL studies
8
SOURCE Chemical inventory jurisdictions
Regulatory lists
4
SOURCE EU CLP Annex VI
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 22 fields
Name
Propyl propionate
CAS Number
106-36-5
DTXSID
DTXSID4042337
Molecular Formula
C6H12O2
InChI Key
MCSINKKTEDDPNK-UHFFFAOYSA-N
Monoisotopic Mass
116.08373
Synonyms
4-02-00-00707BRN 1699993EINECS 203-389-7FEMA No. 2958NSC 72022Propyl propanoaten-Propyl propanoaten-Propyl propionatePropylester kyseliny propionoveUNII-G09TRV00GKFEMA 2958N-Propyl N-propionate

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Flam. Liq. 3; Acute Tox. 4 *H226; H332GHS02; GHS07Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
FragranceFlavouring and nutrientSolvent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
=23.3mg/m3DNEL localinhalationHumanToxValDB GESTIS DNEL
G09TRV00GKUNIIFDA UNII substance identifier--openFDA substances
G09TRV00GKUNIIFDA UNII substance identifier--openFDA substances
G09TRV00GKUNIIFDA UNII substance identifier--openFDA substances
G09TRV00GKUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP ICE skin sensitization
13500ug/cm2Induction dose per skin areaDermalHumanNTP ICE skin sensitization
3unitlessRelative reliability scoreDermalHumanNTP ICE skin sensitization

Showing 8 of 8 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records
StatusNameEC NumberLink
RegisteredPropyl propionate203-389-7ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed CHEMBL3185284
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for Propyl propionate?

Propyl propionate (CAS 106-36-5) is classified under EU CLP Annex VI as Flam. Liq. 3; Acute Tox. 4 * with signal word Warning. Hazard statements: H226; H332. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Propyl propionate?

Propyl propionate has 8 NOAEL studies in the database. The lowest reported value is 23.3 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.

What regulatory lists include Propyl propionate?

Propyl propionate appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.

Is Propyl propionate used in cosmetics?

Yes, Propyl propionate is also indexed as a cosmetic ingredient under the name Propyl Propionate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Propyl propionate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Propyl propionate used outside industrial chemicals?

Propyl propionate also appears in cosmetics, pharmaceutical databases.