Also known as: 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, chloride, Dimethyl Dioctadecylammonium chloride, Distearyl dimethylammonium chloride, NSC 61374, UNII-OM9573ZX3X
CAS 107-64-2
Dimethyldioctadecylammonium chloride (CAS 107-64-2) is a chemical substance with GHS signal word Danger; key hazard signal: H318; H400; H410. Key regulatory status: 11 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.
View cosmetic safety profile for Distearyldimonium Chloride →
Dimethyldioctadecylammonium chloride is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 | H318; H400; H410 | GHS05; GHS09 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| Short-term Effects | The substance is corrosive to the eyes. The substance is irritating to the skin. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 96.3 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 96.3 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 96.3 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 96.3 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| OM9573ZX3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OM9573ZX3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OM9573ZX3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OM9573ZX3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 0.03 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| 0.03 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| 0.03 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| 0.03 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| =11300 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| =13000 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| 90 | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| 90 | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| 90 | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| 90 | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HESS |
| 1 | % | Plateau level | Ocular | - | NTP_ICE_eye_irritation |
| 1 | % | Plateau level | Ocular | - | NTP_ICE_eye_irritation |
| 1 | % | Plateau level | Ocular | - | NTP_ICE_eye_irritation |
| 1 | % | Plateau level | Ocular | - | NTP_ICE_eye_irritation |
Showing 27 of 27 studies
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Dimethyldioctadecylammonium chloride (CAS 107-64-2) is classified under EU CLP Annex VI as Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H318; H400; H410. Source: EU CLP Annex VI (ECHA).
Dimethyldioctadecylammonium chloride has 27 NOAEL studies in the database. The lowest reported value is 96.3 unitless via Ocular in Rabbit. Source: NTP_ICE_eye_irritation.
Dimethyldioctadecylammonium chloride appears on 2 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Yes, Dimethyldioctadecylammonium chloride is also indexed as a cosmetic ingredient under the name Distearyldimonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Dimethyldioctadecylammonium chloride is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Dimethyldioctadecylammonium chloride also appears in cosmetics databases.