What is the GHS hazard classification for 1H-Imidazole, 1-ethenyl-?
1H-Imidazole, 1-ethenyl- (CAS 1072-63-5) is classified under EU CLP Annex VI as Repr. 1B with signal word Danger. Hazard statements: H360D. Source: EU CLP Annex VI (ECHA).
Danger
GHS08
NOAEL Data
SVHC
REACH Registered
Cosmetic Ingredient
1H-Imidazole, 1-ethenyl-
Also known as: EINECS 214-012-0, UNII-ODY9ION63A
CAS 1072-63-5
1H-Imidazole, 1-ethenyl- (CAS 1072-63-5) is a chemical substance with GHS signal word Danger; key hazard signal: H360D. Key regulatory status: SVHC Candidate List, REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ECHA SVHC.
Cross-Vertical Regulatory Divergence
1H-Imidazole, 1-ethenyl- is classified GHS Danger (H360D) in the chemicals database but is restricted in EU cosmetics at max II/1622.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Danger
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
1H-Imidazole, 1-ethenyl-
CAS Number
1072-63-5
DTXSID
DTXSID0061458
Molecular Formula
C5H6N2
InChI Key
OSSNTDFYBPYIEC-UHFFFAOYSA-N
Monoisotopic Mass
94.053098
Synonyms
EINECS 214-012-0UNII-ODY9ION63A
Substance of Very High Concern (SVHC)
Candidate List status and reason under the ECHA REACH SVHC program.
SOURCE
ECHA (EU)
1 records
| Substance | Reason | Included |
|---|---|---|
| 1-vinylimidazole | Toxic for reproduction (Article 57c) | 25-Jun-2020 |
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Repr. 1B | H360D | GHS08 | Danger |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
No specific technical function
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.15 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| ODY9ION63A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ODY9ION63A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ODY9ION63A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ODY9ION63A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1-vinylimidazole | 214-012-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
II/1622
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3929571
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What is the NOAEL for 1H-Imidazole, 1-ethenyl-?
1H-Imidazole, 1-ethenyl- has 5 NOAEL studies in the database. The lowest reported value is 0.15 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
What regulatory lists include 1H-Imidazole, 1-ethenyl-?
1H-Imidazole, 1-ethenyl- appears on 1 regulatory/inventory list including banned; Europe; Personal care. Source: EPA CPDat.
Is 1H-Imidazole, 1-ethenyl- a Substance of Very High Concern (SVHC)?
Yes, 1H-Imidazole, 1-ethenyl- is listed on the ECHA REACH Candidate List as a Substance of Very High Concern. Reason: Toxic for reproduction (Article 57c). Source: ECHA SVHC Candidate List.
Is 1H-Imidazole, 1-ethenyl- used in cosmetics?
Yes, 1H-Imidazole, 1-ethenyl- is also indexed as a cosmetic ingredient under the name N-VINYL IMIDAZOLE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1H-Imidazole, 1-ethenyl- come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ECHA SVHC Candidate List, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 1H-Imidazole, 1-ethenyl- have different safety status in cosmetics vs industrial chemicals?
1H-Imidazole, 1-ethenyl- is classified GHS Danger (H360D) in the chemicals database but is restricted in EU cosmetics at max II/1622.
Is 1H-Imidazole, 1-ethenyl- used outside industrial chemicals?
1H-Imidazole, 1-ethenyl- also appears in cosmetics, pharmaceutical databases.