Warning GHS07GHS09 NOAEL Data REACH Registered Cosmetic Ingredient

3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol

Also known as: Polysantol, 4-Penten-2-ol, 3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-, 3,3-Dimethyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol

CAS 107898-54-4

3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol (CAS 107898-54-4) is a chemical substance with GHS signal word Warning; key hazard signal: H315; H400; H410. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for TRIMETHYLCYCLOPENTENYL DIMETHYLISOPENTENOL →

SOURCE NOAEL studies

NOAEL studies

SOURCE Chemical inventory jurisdictions

Regulatory lists

SOURCE EU CLP Annex VI

GHS signal

Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields

Name

3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol

CAS Number

107898-54-4

Molecular Formula

C15H26O

InChI Key

QZFSNJAQFWEXEA-UHFFFAOYSA-N

Monoisotopic Mass

222.198365

Synonyms

Polysantol4-Penten-2-ol, 3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-3,3-Dimethyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Skin Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1	H315; H400; H410	GHS07; GHS09	Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 41 records

Fragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records

List	Keyword	Source
IFRA Transparency	IFRA	IFRA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 15 of 15 studies

Value	Unit	Endpoint	Route	Species	Source
54.5	%	Concentration, 5% incidence of positive responses	Dermal	Human	NTP ICE skin sensitization
10	%	Concentration, one positive response	Dermal	Human	NTP ICE skin sensitization
0	%	Incidence of positive responses	Dermal	Human	NTP ICE skin sensitization
0.9174	%	Incidence of positive responses	Dermal	Human	NTP ICE skin sensitization
1.000e+4	ug/cm2	Induction dose per skin area	Dermal	Human	NTP ICE skin sensitization
2.725e+4	ug/cm2	Induction dose per skin area, 5% incidence of positive responses	Dermal	Human	NTP ICE skin sensitization
5000	ug/cm2	Induction dose per skin area, one positive response	Dermal	Human	NTP ICE skin sensitization
=300	mg/kg bw/day	NOAEL	oral	Rat	ECHA
3	unitless	Relative reliability score	Dermal	Human	NTP ICE skin sensitization
7.8	%	Viability	Dermal	-	NTP ICE skin irritation
8.83	%	Viability	Dermal	-	NTP ICE skin irritation
9.79	%	Viability	Dermal	-	NTP ICE skin irritation
11.02	%	Viability	Dermal	-	NTP ICE skin irritation
11.71	%	Viability	Dermal	-	NTP ICE skin irritation
14.07	%	Viability	Dermal	-	NTP ICE skin irritation

Showing 15 of 15 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records

Status	Name	EC Number	Link
Registered	(+/-) trans-3,3-dimethyl-5-(2,2,3-trimethyl-cyclopent-3-en-1-yl)pent-4-en-2-ol	411-580-3	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the GHS hazard classification for 3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol?

3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol (CAS 107898-54-4) is classified under EU CLP Annex VI as Skin Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1 with signal word Warning. Hazard statements: H315; H400; H410. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol?

3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol has 15 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP ICE skin sensitization.

What regulatory lists include 3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol?

3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.

Is 3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol used in cosmetics?

Yes, 3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol is also indexed as a cosmetic ingredient under the name TRIMETHYLCYCLOPENTENYL DIMETHYLISOPENTENOL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol used outside industrial chemicals?

3,3-Dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol also appears in cosmetics databases.