Also known as: Ethanol, 2-[(2-aminoethyl)amino]-, 4-04-00-01558, N-Aminoethyl ethanolamine, 2-((2-Aminoethyl)amino)ethanol, N-Aminoethylethanolamine (+12 more)
CAS 111-41-1
N-(Hydroxyethyl)ethylenediamine (CAS 111-41-1) is a chemical substance with GHS signal word Danger; key hazard signal: H360Df; H314; H317. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, EPA TRI.
N-(Hydroxyethyl)ethylenediamine is classified GHS Danger (H360Df, H314, H317) in the chemicals database but is allowed in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Repr. 1B; Skin Corr. 1B; Skin Sens. 1 | H360Df; H314; H317 | GHS08; GHS05; GHS07 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| banned; Europe; Personal care | European Commission | CosIng |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.704 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 15.2 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| 15.2 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| 15.2 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| 15.2 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| RC78W6NPXT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RC78W6NPXT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RC78W6NPXT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RC78W6NPXT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =42598.6 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
| =0.2 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | LOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =250 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 15 of 15 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-(2-aminoethylamino)ethanol | 203-867-5 | ECHA overview → |
TRI hazard and reporting flags for the matched chemical.
| Chemical | Category | Flags |
|---|---|---|
| N-Hydroxyethylethylenediamine | - | - |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →N-(Hydroxyethyl)ethylenediamine (CAS 111-41-1) is classified under EU CLP Annex VI as Repr. 1B; Skin Corr. 1B; Skin Sens. 1 with signal word Danger. Hazard statements: H360Df; H314; H317. Source: EU CLP Annex VI (ECHA).
N-(Hydroxyethyl)ethylenediamine has 15 NOAEL studies in the database. The lowest reported value is 0.704 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
N-(Hydroxyethyl)ethylenediamine appears on 4 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018), inert_ingredient; non_food_use; Pesticides, and 1 more. Source: EPA CPDat.
Yes, N-(Hydroxyethyl)ethylenediamine is also indexed as a cosmetic ingredient under the name Aminoethylethanolamine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
N-(Hydroxyethyl)ethylenediamine is classified GHS Danger (H360Df, H314, H317) in the chemicals database but is allowed in EU cosmetics.
N-(Hydroxyethyl)ethylenediamine also appears in cosmetics, pharmaceutical, cannabis databases.