What is the NOAEL for N,N,N-Trimethyloctadecan-1-aminium chloride?
N,N,N-Trimethyloctadecan-1-aminium chloride has 9 NOAEL studies in the database. The lowest reported value is 91.3 unitless via Ocular in Rabbit. Source: NTP_ICE_eye_irritation.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N,N,N-Trimethyloctadecan-1-aminium chloride
Also known as: 1-Octadecanaminium, N,N,N-trimethyl-, chloride, EINECS 203-929-1, Monostearyl trimethyl ammonium chloride, Quaternium-10, UNII-CZ70647U92
CAS 112-03-8
N,N,N-Trimethyloctadecan-1-aminium chloride (CAS 112-03-8) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
N,N,N-Trimethyloctadecan-1-aminium chloride is classified GHS Danger (H302, H311, H312, H314, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
N,N,N-Trimethyloctadecan-1-aminium chloride
CAS Number
112-03-8
DTXSID
DTXSID1026902
Molecular Formula
C21H46N.ClH
InChI Key
VBIIFPGSPJYLRR-UHFFFAOYSA-M
Monoisotopic Mass
348.339703
Synonyms
1-Octadecanaminium, N,N,N-trimethyl-, chlorideEINECS 203-929-1Monostearyl trimethyl ammonium chlorideQuaternium-10UNII-CZ70647U92
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
PreservativeAnti-static agentSoftener and conditionerStabilizing agentEmulsifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 91.3 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| CZ70647U92 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CZ70647U92 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CZ70647U92 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CZ70647U92 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | unitless | GHS Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 0.32 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| - | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| 57 | % | Plateau level | Ocular | - | NTP_ICE_eye_irritation |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Trimethyloctadecylammonium chloride | 203-929-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TRIMETHYL-OCTADECYL-AMMONIUM CHLORIDE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include N,N,N-Trimethyloctadecan-1-aminium chloride?
N,N,N-Trimethyloctadecan-1-aminium chloride appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is N,N,N-Trimethyloctadecan-1-aminium chloride used in cosmetics?
Yes, N,N,N-Trimethyloctadecan-1-aminium chloride is also indexed as a cosmetic ingredient under the name Steartrimonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N,N,N-Trimethyloctadecan-1-aminium chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does N,N,N-Trimethyloctadecan-1-aminium chloride have different safety status in cosmetics vs industrial chemicals?
N,N,N-Trimethyloctadecan-1-aminium chloride is classified GHS Danger (H302, H311, H312, H314, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
Is N,N,N-Trimethyloctadecan-1-aminium chloride used outside industrial chemicals?
N,N,N-Trimethyloctadecan-1-aminium chloride also appears in cosmetics, pharmaceutical databases.