What is the NOAEL for N,N-Dimethyl-1-hexadecanamine?
N,N-Dimethyl-1-hexadecanamine has 6 NOAEL studies in the database. The lowest reported value is 1 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N,N-Dimethyl-1-hexadecanamine
Also known as: 1-Hexadecanamine, N,N-dimethyl-, Armeen DM 16D, Dimethylhexadecylamine, Dimethylcetylamine, Armeen DM16D (+15 more)
CAS 112-69-6
N,N-Dimethyl-1-hexadecanamine (CAS 112-69-6) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
N,N-Dimethyl-1-hexadecanamine is classified GHS Danger (H302, H314, H318, H400, H410, H335) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
N,N-Dimethyl-1-hexadecanamine
CAS Number
112-69-6
DTXSID
DTXSID9026924
Molecular Formula
C18H39N
InChI Key
NHLUVTZJQOJKCC-UHFFFAOYSA-N
Monoisotopic Mass
269.30825
Synonyms
1-Hexadecanamine, N,N-dimethyl-Armeen DM 16DDimethylhexadecylamineDimethylcetylamineArmeen DM16DBairdcat B16BRN 1755921CetyldimethylamineN,N-DimethylcetylamineDimethyl-n-hexadecylamineN,N-DimethylhexadecylamineN,N-Dimethyl-n-hexadecylamine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Anti-static agentEmulsifierSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Vehicle - car interior - auto air freshener | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 5E4QI660PW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5E4QI660PW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5E4QI660PW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5E4QI660PW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexadecyldimethylamine | 203-997-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1877748
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include N,N-Dimethyl-1-hexadecanamine?
N,N-Dimethyl-1-hexadecanamine appears on 3 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, detected; Europe; Toys and children's products, air; detected; emissions; Europe; Vehicle - car interior - auto air freshener. Source: EPA CPDat.
Is N,N-Dimethyl-1-hexadecanamine used in cosmetics?
Yes, N,N-Dimethyl-1-hexadecanamine is also indexed as a cosmetic ingredient under the name Dimethyl Palmitamine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N,N-Dimethyl-1-hexadecanamine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does N,N-Dimethyl-1-hexadecanamine have different safety status in cosmetics vs industrial chemicals?
N,N-Dimethyl-1-hexadecanamine is classified GHS Danger (H302, H314, H318, H400, H410, H335) in the chemicals database but is restricted in EU cosmetics.
Is N,N-Dimethyl-1-hexadecanamine used outside industrial chemicals?
N,N-Dimethyl-1-hexadecanamine also appears in cosmetics, pharmaceutical databases.