What is the NOAEL for Guanosine?
Guanosine has 4 NOAEL studies in the database. The lowest reported value is 12133JR80S UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Guanosine
Also known as: 2-Amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-, 7: PN: WO2013104540 PAGE: 124 claimed sequence, DL-Guanosine, Guanine ribonucleoside (+8 more)
CAS 118-00-3
Guanosine (CAS 118-00-3) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Guanosine is classified GHS Danger (H301) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
Guanosine
CAS Number
118-00-3
DTXSID
DTXSID00893055
Molecular Formula
C10H13N5O5
InChI Key
NYHBQMYGNKIUIF-UUOKFMHZSA-N
Monoisotopic Mass
283.091669
Synonyms
2-Amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-7: PN: WO2013104540 PAGE: 124 claimed sequenceDL-GuanosineGuanine ribonucleosideGuanine, 9-β-D-ribofuranosyl-Inosine, 2-amino-NSC 19994Vernineβ-D-Ribofuranoside, guanine-9guanosinaGuanosin
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
Softener and conditionerOpacifer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 12133JR80S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12133JR80S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12133JR80S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12133JR80S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GUANOSINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include Guanosine?
Guanosine appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Guanosine used in cosmetics?
Yes, Guanosine is also indexed as a cosmetic ingredient under the name Guanosine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Guanosine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Guanosine have different safety status in cosmetics vs industrial chemicals?
Guanosine is classified GHS Danger (H301) in the chemicals database but is allowed in EU cosmetics.
Is Guanosine used outside industrial chemicals?
Guanosine also appears in cosmetics, pharmaceutical databases.