What is the NOAEL for 3,3-Dimethylallyl acetate?
3,3-Dimethylallyl acetate has 11 NOAEL studies in the database. The lowest reported value is 5.77 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3,3-Dimethylallyl acetate
Also known as: 4-02-00-00185, BRN 1746265, Dimethylallyl acetate, EINECS 214-730-4, Isopent-2-enyl acetate (+2 more)
CAS 1191-16-8
3,3-Dimethylallyl acetate (CAS 1191-16-8) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
3,3-Dimethylallyl acetate
CAS Number
1191-16-8
DTXSID
DTXSID9047128
Molecular Formula
C7H12O2
InChI Key
XXIKYCPRDXIMQM-UHFFFAOYSA-N
Monoisotopic Mass
128.08373
Synonyms
4-02-00-00185BRN 1746265Dimethylallyl acetateEINECS 214-730-4Isopent-2-enyl acetate3-Methyl-2-buten-1-ol, acetateUNII-I7KOV03HGS
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| air; Cleaning products and household care - laundry and fabric treatment; detected; emissions | Elsevier | CPCat |
| air; detected; emissions; Personal care | Elsevier | CPCat |
| air; Cleaning products and household care - air freshener; detected; emissions | Elsevier | CPCat |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =5.77 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| I7KOV03HGS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I7KOV03HGS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I7KOV03HGS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I7KOV03HGS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2326 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 13500 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =2900 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-methyl-2-butenyl acetate | 214-730-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3560443
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3,3-Dimethylallyl acetate?
3,3-Dimethylallyl acetate appears on 8 regulatory/inventory lists including air; Cleaning products and household care - laundry and fabric treatment; detected; emissions, air; detected; emissions; Personal care, air; Cleaning products and household care - air freshener; detected; emissions, and 5 more. Source: EPA CPDat.
Is 3,3-Dimethylallyl acetate used in cosmetics?
Yes, 3,3-Dimethylallyl acetate is also indexed as a cosmetic ingredient under the name 3-Isopentenyl Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3,3-Dimethylallyl acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3,3-Dimethylallyl acetate used outside industrial chemicals?
3,3-Dimethylallyl acetate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.