What is the NOAEL for 3-Phenylpropyl cinnamate?
3-Phenylpropyl cinnamate has 8 NOAEL studies in the database. The lowest reported value is F0Q8B0FS94 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3-Phenylpropyl cinnamate
Also known as: 2-Propenoic acid, 3-phenyl-, 3-phenylpropyl ester, Cinnamic acid, 3-phenylpropyl ester, EINECS 204-565-6, FEMA No. 2894, Hydrocinnamyl cinnamate (+6 more)
CAS 122-68-9
3-Phenylpropyl cinnamate (CAS 122-68-9) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
3-Phenylpropyl cinnamate
CAS Number
122-68-9
DTXSID
DTXSID9047411
Molecular Formula
C18H18O2
InChI Key
LYRAHIUDQRJGGZ-UHFFFAOYSA-N
Monoisotopic Mass
266.13068
Synonyms
2-Propenoic acid, 3-phenyl-, 3-phenylpropyl esterCinnamic acid, 3-phenylpropyl esterEINECS 204-565-6FEMA No. 2894Hydrocinnamyl cinnamateHydrocinnamyl 3-phenylpropenoate3-Phenyl-2-propenoic acid 3-phenylpropyl esterPhenylpropyl cinnamate3-Phenylpropyl beta-phenylacrylate3-Phenylpropyl 3-phenyl-2-propenoateUNII-F0Q8B0FS94
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| F0Q8B0FS94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F0Q8B0FS94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F0Q8B0FS94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F0Q8B0FS94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3-Phenylpropyl cinnamate?
3-Phenylpropyl cinnamate appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is 3-Phenylpropyl cinnamate used in cosmetics?
Yes, 3-Phenylpropyl cinnamate is also indexed as a cosmetic ingredient under the name Hydrocinnamyl Cinnamate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Phenylpropyl cinnamate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Phenylpropyl cinnamate used outside industrial chemicals?
3-Phenylpropyl cinnamate also appears in cosmetics, food safety, cannabis databases.