What is the NOAEL for C.I. Basic Blue 41?
C.I. Basic Blue 41 has 5 NOAEL studies in the database. The lowest reported value is 0.219 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
C.I. Basic Blue 41
Also known as: 2-[[4-[Ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methylbenzothiazolium methyl sulfate, Benzothiazolium, 2-[2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]diazenyl]-6-methoxy-3-methyl-, methyl sulfate (1:1), Benzothiazolium, 2-[[4-[ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methyl-, methyl sulfate (salt), C.I. 11105, EC No.: 235-546-0 (+15 more)
CAS 12270-13-2
C.I. Basic Blue 41 (CAS 12270-13-2) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
C.I. Basic Blue 41 is classified GHS Danger (H302, H314, H315, H318, H319, H335, H373, H400) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
C.I. Basic Blue 41
CAS Number
12270-13-2
DTXSID
DTXSID3051624
Molecular Formula
C19H23N4O2S.CH4O4S
InChI Key
MHOFGBJTSNWTDT-UHFFFAOYSA-M
Monoisotopic Mass
483.137202
Synonyms
2-[[4-[Ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methylbenzothiazolium methyl sulfateBenzothiazolium, 2-[2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]diazenyl]-6-methoxy-3-methyl-, methyl sulfate (1:1)Benzothiazolium, 2-[[4-[ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methyl-, methyl sulfate (salt)C.I. 11105EC No.: 235-546-0EINECS 235-546-0UNII-1ECX0J387PAizen Cathilon Blue GRLHAnilan Blue GRLApollo Cationic Blue GRLAstrazon Blue FGGLBB 41
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.219 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 1ECX0J387P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1ECX0J387P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1ECX0J387P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1ECX0J387P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-[[4-[ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methylbenzothiazolium methyl sulphate | 235-546-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BASIC BLUE 41
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include C.I. Basic Blue 41?
C.I. Basic Blue 41 appears on 2 regulatory/inventory lists including banned; Europe; Personal care, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is C.I. Basic Blue 41 used in cosmetics?
Yes, C.I. Basic Blue 41 is also indexed as a cosmetic ingredient under the name Basic Blue 75. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Basic Blue 41 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does C.I. Basic Blue 41 have different safety status in cosmetics vs industrial chemicals?
C.I. Basic Blue 41 is classified GHS Danger (H302, H314, H315, H318, H319, H335, H373, H400) in the chemicals database but is allowed in EU cosmetics.
Is C.I. Basic Blue 41 used outside industrial chemicals?
C.I. Basic Blue 41 also appears in cosmetics, pharmaceutical databases.