What is the NOAEL for Allyl hexanoate?
Allyl hexanoate has 26 NOAEL studies in the database. The lowest reported value is 0.13 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Allyl hexanoate
Also known as: Hexanoic acid, 2-propen-1-yl ester, 4-02-00-00924, BRN 1761920, EINECS 204-642-4, FEMA No. 2032 (+4 more)
CAS 123-68-2
Allyl hexanoate (CAS 123-68-2) is a chemical substance. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Allyl hexanoate is classified GHS Danger (H301, H311, H315, H319, H331, H400, H410, H411) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
26
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Allyl hexanoate
CAS Number
123-68-2
DTXSID
DTXSID1047653
Molecular Formula
C9H16O2
InChI Key
RCSBILYQLVXLJG-UHFFFAOYSA-N
Monoisotopic Mass
156.11503
Synonyms
Hexanoic acid, 2-propen-1-yl ester4-02-00-00924BRN 1761920EINECS 204-642-4FEMA No. 2032NSC 209622-Propenyl n-hexanoateAllylester kyseliny kapronoveUNII-3VH84A363D
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceSoftener and conditionerAstringentDeodorizerFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care; restricted | European Commission | CosIng |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 26 of 26 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=0.13 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| =15 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 3VH84A363D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3VH84A363D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3VH84A363D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3VH84A363D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =218 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =50 | mg/kg bw/day | LEL | oral | Chicken | ToxValDB_EFSA |
| =75 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =35 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 65 | mg/kg bw/day | LOAEL | oral | rat | COSMOS_DB |
| =65 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =12 | mg/kg bw/day | LOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 12 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 15 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 65 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 100 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 125 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| >195 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >214 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 250 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =15 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =78 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 26 of 26 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Allyl hexanoate | 204-642-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ALLYL HEXANOATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Allyl hexanoate?
Allyl hexanoate appears on 6 regulatory/inventory lists including Europe; Personal care; restricted, IFRA Transparency, Europe, and 3 more. Source: EPA CPDat.
Is Allyl hexanoate used in cosmetics?
Yes, Allyl hexanoate is also indexed as a cosmetic ingredient under the name Allyl Caproate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Allyl hexanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Allyl hexanoate have different safety status in cosmetics vs industrial chemicals?
Allyl hexanoate is classified GHS Danger (H301, H311, H315, H319, H331, H400, H410, H411) in the chemicals database but is restricted in EU cosmetics.
Is Allyl hexanoate used outside industrial chemicals?
Allyl hexanoate also appears in cosmetics, pharmaceutical, cannabis databases.