NOAEL Data Cosmetic Ingredient

Polyquaternium-51

Also known as: 2-[(2-Methylprop-2-enoyl)oxy]ethyl 2-(trimethylazaniumyl)ethyl phosphate--butyl 2-methylprop-2-enoate (1/1), 3,5,8-Trioxa-4-phosphaundec-10-en-1-aminium, 4-hydroxy-N,N,N,10- tetramethyl-9-oxo-, inner salt, 4-oxide, polymer with butyl 2-methyl-2- propenoate, 2-Propenoic acid, 2-methyl-, butyl ester, polymer with 4-hydroxy- N,N,N,10-tetramethyl-9-oxo-3,5,8-trioxa-4-phosphaundec-10-en-1-aminium inner salt 4-oxide, 2-Methacryloyloxyethylphosphorylcholine-butyl methacrylate copolymer, Butyl methacrylate-2-(methacryloyloxy)ethyl-2'- (trimethylammonio)ethyl phosphate copolymer (+4 more)

CAS 125275-25-4

Polyquaternium-51 (CAS 125275-25-4) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Polyquaternium-51 →

SOURCE noael studies public
NOAEL studies
8
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Polyquaternium-51
CAS Number
125275-25-4
DTXSID
DTXSID40925061
Synonyms
2-[(2-Methylprop-2-enoyl)oxy]ethyl 2-(trimethylazaniumyl)ethyl phosphate--butyl 2-methylprop-2-enoate (1/1)3,5,8-Trioxa-4-phosphaundec-10-en-1-aminium, 4-hydroxy-N,N,N,10- tetramethyl-9-oxo-, inner salt, 4-oxide, polymer with butyl 2-methyl-2- propenoate2-Propenoic acid, 2-methyl-, butyl ester, polymer with 4-hydroxy- N,N,N,10-tetramethyl-9-oxo-3,5,8-trioxa-4-phosphaundec-10-en-1-aminium inner salt 4-oxide2-Methacryloyloxyethylphosphorylcholine-butyl methacrylate copolymerButyl methacrylate-2-(methacryloyloxy)ethyl-2'- (trimethylammonio)ethyl phosphate copolymerButyl methacrylate-2- methacryloyloxyethylphosphorylcholine copolymerLipidure PMBn-Butyl methacrylate-2-methacryloyloxyethylphosphorylcholine2-(N,N,N-trimethylamino)ethyl 2-(2-methyl-2-propenoyloxy)ethyl phosphate inner salt, polymer with butyl 2-methyl-2-propenoate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records
Film formerSoftener and conditionerHumectant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
EL9825H96JUNIIFDA UNII substance identifier--openFDA substances
EL9825H96JUNIIFDA UNII substance identifier--openFDA substances
EL9825H96JUNIIFDA UNII substance identifier--openFDA substances
EL9825H96JUNIIFDA UNII substance identifier--openFDA substances
X8Q92E1CPMUNIIFDA UNII substance identifier--openFDA substances
X8Q92E1CPMUNIIFDA UNII substance identifier--openFDA substances
X8Q92E1CPMUNIIFDA UNII substance identifier--openFDA substances
X8Q92E1CPMUNIIFDA UNII substance identifier--openFDA substances

Showing 8 of 8 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Polyquaternium-51?

Polyquaternium-51 has 8 NOAEL studies in the database. The lowest reported value is EL9825H96J UNII. Source: openFDA substances.

Is Polyquaternium-51 used in cosmetics?

Yes, Polyquaternium-51 is also indexed as a cosmetic ingredient under the name Polyquaternium-51. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Polyquaternium-51 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Polyquaternium-51 used outside industrial chemicals?

Polyquaternium-51 also appears in cosmetics databases.