NOAEL Data REACH Registered Cosmetic Ingredient

2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate

Also known as: Trioctyldodecyl citrate

CAS 126121-35-5

2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate (CAS 126121-35-5) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Trioctyldodecyl Citrate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields
Name
2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate
CAS Number
126121-35-5
DTXSID
DTXSID70925418
Molecular Formula
C42H80O7
InChI Key
RIICSBODUUINQE-UHFFFAOYSA-L
Monoisotopic Mass
696.590405
Synonyms
Trioctyldodecyl citrate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
Softener and conditionerHumectant

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
Canada; Personal care; Substances in PCP - Canada (4/2014)Government of CanadaCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
35X8CT063RUNIIFDA UNII substance identifier--openFDA substances
35X8CT063RUNIIFDA UNII substance identifier--openFDA substances
35X8CT063RUNIIFDA UNII substance identifier--openFDA substances
35X8CT063RUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registeredtris(2-octyldodecyl) citrate603-121-2ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate?

2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate has 4 NOAEL studies in the database. The lowest reported value is 35X8CT063R UNII. Source: openFDA substances.

What regulatory lists include 2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate?

2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate appears on 1 regulatory/inventory list including Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.

Is 2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate used in cosmetics?

Yes, 2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate is also indexed as a cosmetic ingredient under the name Trioctyldodecyl Citrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate used outside industrial chemicals?

2-{2-[(9,10-Dioctylicosan-9-yl)oxy]-2-oxoethyl}-2-hydroxybutanedioate also appears in cosmetics databases.