What is the NOAEL for Ursodeoxycholic acid?
Ursodeoxycholic acid has 5 NOAEL studies in the database. The lowest reported value is 724L30Y2QR UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ursodeoxycholic acid
Also known as: Ursodiol, Ursodesoxycholic acid, Ursocholic acid, deoxy-, Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7β)-, (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid (+14 more)
CAS 128-13-2
Ursodeoxycholic acid (CAS 128-13-2) is a chemical substance. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Ursodeoxycholic acid
CAS Number
128-13-2
DTXSID
DTXSID6023731
Molecular Formula
C24H40O4
InChI Key
RUDATBOHQWOJDD-UZVSRGJWSA-N
Monoisotopic Mass
392.29266
Synonyms
UrsodiolUrsodesoxycholic acidUrsocholic acid, deoxy-Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7β)-(3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid4-10-00-01604BRN 32198883-alpha,7-beta-Dihydroxy-5-beta-cholanoic acidEINECS 204-879-37-beta-Hydroxylithocholic acid17-beta-(1-Methyl-3-carboxypropyl)etiocholane-3-alpha,7-beta-diolPeptarom
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
HumectantSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 724L30Y2QR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 724L30Y2QR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 724L30Y2QR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 724L30Y2QR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =4600 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ursodeoxycholic acid | 204-879-3 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
URSODIOL
ChEMBL Phase
4
Adverse Events
3285
Bioactivity
15
Frequently Asked Questions
What regulatory lists include Ursodeoxycholic acid?
Ursodeoxycholic acid appears on 3 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Ursodeoxycholic acid used in cosmetics?
Yes, Ursodeoxycholic acid is also indexed as a cosmetic ingredient under the name Ursodiol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ursodeoxycholic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Ursodeoxycholic acid used outside industrial chemicals?
Ursodeoxycholic acid also appears in cosmetics, pharmaceutical databases.