What is the GHS hazard classification for Phosphorus pentoxide?
Phosphorus pentoxide (CAS 1314-56-3) is classified under EU CLP Annex VI as Skin Corr. 1A with signal word Danger. Hazard statements: H314. Source: EU CLP Annex VI (ECHA).
Danger
GHS05
NOAEL Data
REACH Registered
Cosmetic Ingredient
Phosphorus pentoxide
Also known as: Diphosphorus pentaoxide, Diphosphorus pentoxide, Phosphoric acid anhydride, PHOSPHORIC ANHYDRIDE, Phosphoric oxide (+11 more)
CAS 1314-56-3
Phosphorus pentoxide (CAS 1314-56-3) is a chemical substance with GHS signal word Danger; key hazard signal: H314. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Phosphorus pentoxide is classified GHS Danger (H314) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Danger
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Phosphorus pentoxide
CAS Number
1314-56-3
DTXSID
DTXSID9047754
Molecular Formula
O10P4
InChI Key
DLYUQMMRRRQYAE-UHFFFAOYSA-N
Monoisotopic Mass
283.844194
Synonyms
Diphosphorus pentaoxideDiphosphorus pentoxidePhosphoric acid anhydridePHOSPHORIC ANHYDRIDEPhosphoric oxidePhosphoric pentoxidePhosphorus pentaoxideDiphosphorus pentaoxide (P2O5)DiphosphorpentaoxidPHOSPHORUS OXIDEEINECS 215-236-1Phosphoric acid, anhydrous
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Skin Corr. 1A | H314 | GHS05 | Danger |
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
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ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is very corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of dust may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
Chelating agentpH regulating agentFlame retardantCatalyst
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 51SWB7223J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 51SWB7223J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 51SWB7223J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 51SWB7223J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1.217 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Diphosphorus pentaoxide | 215-236-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
What is the NOAEL for Phosphorus pentoxide?
Phosphorus pentoxide has 6 NOAEL studies in the database. The lowest reported value is 1 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
What regulatory lists include Phosphorus pentoxide?
Phosphorus pentoxide appears on 1 regulatory/inventory list including Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Phosphorus pentoxide used in cosmetics?
Yes, Phosphorus pentoxide is also indexed as a cosmetic ingredient under the name Phosphorus Pentoxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Phosphorus pentoxide come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Phosphorus pentoxide have different safety status in cosmetics vs industrial chemicals?
Phosphorus pentoxide is classified GHS Danger (H314) in the chemicals database but is allowed in EU cosmetics.
Is Phosphorus pentoxide used outside industrial chemicals?
Phosphorus pentoxide also appears in cosmetics databases.