What is the NOAEL for 2,6-Dimethyl-2-heptanol?
2,6-Dimethyl-2-heptanol has 15 NOAEL studies in the database. The lowest reported value is 4.02 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,6-Dimethyl-2-heptanol
Also known as: 2-Heptanol, 2,6-dimethyl-, 2-01-00-00457, BRN 1733525, 2,6-Dimethylheptan-2-ol, Dimetol (+4 more)
CAS 13254-34-7
2,6-Dimethyl-2-heptanol (CAS 13254-34-7) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
15
SOURCE
Chemical inventory jurisdictions
Regulatory lists
5
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
2,6-Dimethyl-2-heptanol
CAS Number
13254-34-7
DTXSID
DTXSID6041424
Molecular Formula
C9H20O
InChI Key
HGDVHRITTGWMJK-UHFFFAOYSA-N
Monoisotopic Mass
144.151415
Synonyms
2-Heptanol, 2,6-dimethyl-2-01-00-00457BRN 17335252,6-Dimethylheptan-2-olDimetolEINECS 236-244-1FreesiolLolitolUNII-991142090Z
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
46 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| air; detected; emissions; Personal care | Elsevier | CPCat |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 15 of 15 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =10.05 | mg/m3 | DNEL local | inhalation | Human | ToxValDB GESTIS DNEL |
| =4.02 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 991142090Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 991142090Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 991142090Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 991142090Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 3100 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 6750 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| =6800 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| - | unitless | Model Score | - | - | NTP ICE endocrine |
| =3000 | ppm | NOAEL | oral | Rat | ECHA |
| =10000 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 15 of 15 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,6-dimethylheptan-2-ol | 236-244-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHEMBL3187118
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2,6-Dimethyl-2-heptanol?
2,6-Dimethyl-2-heptanol appears on 5 regulatory/inventory lists including air; detected; emissions; Personal care, IFRA Transparency, Europe, and 2 more. Source: EPA CPDat.
Is 2,6-Dimethyl-2-heptanol used in cosmetics?
Yes, 2,6-Dimethyl-2-heptanol is also indexed as a cosmetic ingredient under the name 2,6-Dimethylheptanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,6-Dimethyl-2-heptanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,6-Dimethyl-2-heptanol used outside industrial chemicals?
2,6-Dimethyl-2-heptanol also appears in cosmetics, pharmaceutical, cannabis databases.