Also known as: (NH4)(OH), Ammonium hydroxide ((NH4)(OH)), Ammonia water 29%, Aquammonia, Caswell No. 044 (+12 more)
CAS 1336-21-6
Ammonium hydroxide (CAS 1336-21-6) is a chemical substance with GHS signal word Danger; key hazard signal: H314; H400. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Ammonium hydroxide is classified GHS Danger (H314, H400) in the chemicals database but is restricted in EU cosmetics at max 6% as NH3.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Skin Corr. 1B; Aquatic Acute 1 | H314; H400 | GHS05; GHS09 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | May be osive to metals Harmful if swallowed Causes severe skin burns and eye damage May cause respiratory irritation Very toxic to aquatic life |
| Short-term Effects | The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of high concentrations of the vapour may cause laryngeal oedema, inflammation of the respiratory tract and pneumonia. Exposure could cause asphyxiation due to swelling in the throat. The effects may be delayed. |
| Long-term Effects | Repeated or prolonged inhalation may cause effects on the lungs. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol or vapour and by ingestion. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe | Danish Environmental Protection Agency | Danish EPA |
| Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| Europe; Specialty occupational products | Danish Environmental Protection Agency | Danish EPA |
| inert_ingredient; Pesticides | EPA | CPCat |
| Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ammonia, aqueous solution | 215-647-6 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS food additive, ADI, and GRAS records where available.
E527 — ADI: NOT LIMITED mg/kg bw
View full food safety profile →Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →Ammonium hydroxide (CAS 1336-21-6) is classified under EU CLP Annex VI as Skin Corr. 1B; Aquatic Acute 1 with signal word Danger. Hazard statements: H314; H400. Source: EU CLP Annex VI (ECHA).
Ammonium hydroxide has 4 NOAEL studies in the database. The lowest reported value is concept identifier. Source: openFDA substances.
Ammonium hydroxide appears on 9 regulatory/inventory lists including Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe, Europe; Vehicle - car interior, Europe; Specialty occupational products, and 6 more. Source: EPA CPDat.
Yes, Ammonium hydroxide is also indexed as a cosmetic ingredient under the name Ammonium Hydroxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Ammonium hydroxide is classified GHS Danger (H314, H400) in the chemicals database but is restricted in EU cosmetics at max 6% as NH3.
Ammonium hydroxide also appears in cosmetics, food safety, cannabis databases.