NOAEL Data REACH Registered Cosmetic Ingredient

Copper sodium ethylenediaminetetraacetate (1:2:1)

Also known as: Cuprate(2-), [[N,N'-1,2-ethanediylbis[N-[(carboxy-kO)methyl]glycinato-kN,kO]](4-)]-, sodium (1:2), (OC-6-21)-, Cuprate(2-), [(ethylenedinitrilo)tetraacetato]-, disodium, Cuprate(2-), [[N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycinato]](4-)- N,N',O,O',ON,ON']-, disodium, (OC-6-21)-, Cuprate(2-), [[N,N'-1,2-ethanediylbis[N-[(carboxy-kO)methyl]glycinato-kN,kO]](4-)]-, disodium, (OC-6-21)-, Sodium [(ethylenedinitrilo)tetraacetato]cuprate(II) (+10 more)

CAS 14025-15-1

Copper sodium ethylenediaminetetraacetate (1:2:1) (CAS 14025-15-1) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Disodium EDTA-Copper →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 21 fields

Name

Copper sodium ethylenediaminetetraacetate (1:2:1)

CAS Number

14025-15-1

DTXSID

DTXSID10893248

Molecular Formula

C10H16N2O8.Cu.2Na

InChI Key

SPLGNGVLDOVUHY-UHFFFAOYSA-J

Monoisotopic Mass

400.999802

Synonyms

Cuprate(2-), [[N,N'-1,2-ethanediylbis[N-[(carboxy-kO)methyl]glycinato-kN,kO]](4-)]-, sodium (1:2), (OC-6-21)-Cuprate(2-), [(ethylenedinitrilo)tetraacetato]-, disodiumCuprate(2-), [[N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycinato]](4-)- N,N',O,O',ON,ON']-, disodium, (OC-6-21)-Cuprate(2-), [[N,N'-1,2-ethanediylbis[N-[(carboxy-kO)methyl]glycinato-kN,kO]](4-)]-, disodium, (OC-6-21)-Sodium [(ethylenedinitrilo)tetraacetato]cuprate(II)Bovi-CuChelest Cu 40Copper disodium EDTACopper disodium ethylenediaminetetraacetateDisodium (ethylenediaminetetraacetato)cuprate(2-)Disodium cupric EDTAEDTA copper disodium salt

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records

AstringentChelating agentDye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records

List	Keyword	Source
Personal care	FDA	United States Food and Drug Administration (FDA)
inert_ingredient; Pesticides	EPA	CPCat
inert_ingredient; non_food_use; Pesticides	EPA	CPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies

Value	Unit	Endpoint	Route	Species	Source
=1.8	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
6V475AX06U	UNII	FDA UNII substance identifier	-	-	openFDA substances
6V475AX06U	UNII	FDA UNII substance identifier	-	-	openFDA substances
6V475AX06U	UNII	FDA UNII substance identifier	-	-	openFDA substances
6V475AX06U	UNII	FDA UNII substance identifier	-	-	openFDA substances
=150	mg/kg bw/day	LOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
~150	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
>=500	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID

Showing 8 of 8 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Disodium [[N,N'-ethylenebis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',ON,ON']cuprate(2-)	237-864-5	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

< 0.5%

Frequently Asked Questions

What is the NOAEL for Copper sodium ethylenediaminetetraacetate (1:2:1)?

Copper sodium ethylenediaminetetraacetate (1:2:1) has 8 NOAEL studies in the database. The lowest reported value is 1.8 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Copper sodium ethylenediaminetetraacetate (1:2:1)?

Copper sodium ethylenediaminetetraacetate (1:2:1) appears on 3 regulatory/inventory lists including Personal care, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is Copper sodium ethylenediaminetetraacetate (1:2:1) used in cosmetics?

Yes, Copper sodium ethylenediaminetetraacetate (1:2:1) is also indexed as a cosmetic ingredient under the name Disodium EDTA-Copper. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Copper sodium ethylenediaminetetraacetate (1:2:1) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Copper sodium ethylenediaminetetraacetate (1:2:1) used outside industrial chemicals?

Copper sodium ethylenediaminetetraacetate (1:2:1) also appears in cosmetics databases.