What is the NOAEL for Citronellyl propionate?
Citronellyl propionate has 20 NOAEL studies in the database. The lowest reported value is 87R1092U7J UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Citronellyl propionate
Also known as: Citronellyl propanoate, 3,7-Dimethyl-6-octen-1-ol propanoate, 3,7-Dimethyl-6-octen-1-yl propanoate, 3,7-Dimethyl-6-octen-1-yl propionate, EINECS 205-461-3 (+5 more)
CAS 141-14-0
Citronellyl propionate (CAS 141-14-0) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
20
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Citronellyl propionate
CAS Number
141-14-0
DTXSID
DTXSID8047187
Molecular Formula
C13H24O2
InChI Key
POPNTVRHTZDEBW-UHFFFAOYSA-N
Monoisotopic Mass
212.17763
Synonyms
Citronellyl propanoate3,7-Dimethyl-6-octen-1-ol propanoate3,7-Dimethyl-6-octen-1-yl propanoate3,7-Dimethyl-6-octen-1-yl propionateEINECS 205-461-3EINECS 278-466-1FEMA No. 23166-Octen-1-ol, 3,7-dimethyl-, propionatePropionic acid, ester with citronellolUNII-87R1092U7J
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 20 of 20 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 87R1092U7J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 87R1092U7J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 87R1092U7J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 87R1092U7J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_EFSA |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 20 of 20 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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EMBL-EBI ChEMBL
CHEMBL3185956
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Citronellyl propionate?
Citronellyl propionate appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Citronellyl propionate used in cosmetics?
Yes, Citronellyl propionate is also indexed as a cosmetic ingredient under the name Citronellyl Propionate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Citronellyl propionate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Citronellyl propionate used outside industrial chemicals?
Citronellyl propionate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.