What is the NOAEL for Sodium formate?
Sodium formate has 19 NOAEL studies in the database. The lowest reported value is 35.26 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium formate
Also known as: EINECS 205-488-0, FORMIC ACID, NA SALT, NSC 77457, Salachlor, Mravencan sodny (+3 more)
CAS 141-53-7
Sodium formate (CAS 141-53-7) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
SOURCE
noael studies public
NOAEL studies
19
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
13 fields
Name
Sodium formate
CAS Number
141-53-7
DTXSID
DTXSID2027090
Molecular Formula
CH2O2.Na
InChI Key
HLBBKKJFGFRGMU-UHFFFAOYSA-M
Synonyms
EINECS 205-488-0FORMIC ACID, NA SALTNSC 77457SalachlorMravencan sodnyUNII-387AD98770Sodium methanoatesodium formiate
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes and respiratory tract. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Stabilizing agentPreservativepH regulating agentChelating agentProcessing aids not otherwise specified
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe | Danish EPA | Danish EPA |
| Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe | Danish EPA | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 19 of 19 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =35.26 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 387AD98770 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 387AD98770 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 387AD98770 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 387AD98770 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.00003 | mg | LOEL | injection | Mouse | ToxValDB_ECOTOX |
| =0.00101 | mg | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =0.00151 | mg | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =0.5 | mg/mL | LOEL | environmental | Mouse | ToxValDB_ECOTOX |
| =2 | mg/mL | LOEL | environmental | Rat | ToxValDB_ECOTOX |
| =4 | mg/mL | LOEL | environmental | Mouse | ToxValDB_ECOTOX |
| =750 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =945 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =0.00003 | mg | NOEL | injection | Rat | ToxValDB_ECOTOX |
| =0.00051 | mg | NOEL | injection | Rat | ToxValDB_ECOTOX |
| =0.00101 | mg | NOEL | injection | Rat | ToxValDB_ECOTOX |
| =1 | mg/mL | NOEL | environmental | Rat | ToxValDB_ECOTOX |
| =2 | mg/mL | NOEL | environmental | Mouse | ToxValDB_ECOTOX |
Showing 19 of 19 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium formate | 205-488-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SODIUM FORMATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
2 records
E237 — ADI: 3 mg/kg bw | FDA GRAS: FDA has no questions
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium formate?
Sodium formate appears on 7 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, active_ingredient; Europe; Pesticides, Europe; Personal care - hair styling and care - shampoo-dandruff, and 4 more. Source: EPA CPDat.
Is Sodium formate used in cosmetics?
Yes, Sodium formate is also indexed as a cosmetic ingredient under the name Sodium Formate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium formate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium formate used outside industrial chemicals?
Sodium formate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.