What is the NOAEL for 1-Nonanol?
1-Nonanol has 18 NOAEL studies in the database. The lowest reported value is 118 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1-Nonanol
Also known as: 4-01-00-01798, BRN 0969213, EINECS 205-583-7, Fatty alcohol(C9), FEMA No. 2789 (+7 more)
CAS 143-08-8
1-Nonanol (CAS 143-08-8) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
18
SOURCE
Chemical inventory jurisdictions
Regulatory lists
10
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
1-Nonanol
CAS Number
143-08-8
DTXSID
DTXSID6022008
Molecular Formula
C9H20O
InChI Key
ZWRUINPWMLAQRD-UHFFFAOYSA-N
Monoisotopic Mass
144.151415
Synonyms
4-01-00-01798BRN 0969213EINECS 205-583-7Fatty alcohol(C9)FEMA No. 2789UNII-NGK73Q6XMCAcovenoside cAlcohol C9FEMA 2789Nonyl alcohol, 8CInonan-1-olNonanol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Europe | European Commission | Fl@vis |
| Canada; pharmaceutical | DrugBank | DrugBank |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; Cleaning products and household care - air freshener; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 18 of 18 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =118 | mg/m3 | DNEL local | inhalation | Human | ToxValDB GESTIS DNEL |
| =176 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| NGK73Q6XMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NGK73Q6XMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NGK73Q6XMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NGK73Q6XMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 1296 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| =3200 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =3560 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =3000 | mg/kg bw/day | LEL | oral | Rat | ECHA |
| =47201.2 | mg/m3 | LEL | inhalation | Human | ToxValDB DOE Protective Action Criteria |
| - | unitless | Model Score | - | - | NTP ICE endocrine |
| =150 | mg/m3 | NOAEC | inhalation | Rat | ECHA |
| =1440 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
| 1.5 | kiloohms | TER | Dermal | - | NTP ICE skin irritation |
| 2.5 | kiloohms | TER | Dermal | - | NTP ICE skin irritation |
Showing 18 of 18 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Nonan-1-ol | 205-583-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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ChEMBL / DailyMed
NONANOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1-Nonanol?
1-Nonanol appears on 9 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, SCIL (9/2019), Europe, and 6 more. Source: EPA CPDat.
Is 1-Nonanol used in cosmetics?
Yes, 1-Nonanol is also indexed as a cosmetic ingredient under the name NONYL ALCOHOL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-Nonanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1-Nonanol used outside industrial chemicals?
1-Nonanol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.