What is the NOAEL for Erythritol?
Erythritol has 9 NOAEL studies in the database. The lowest reported value is RA96B954X6 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Erythritol
Also known as: Erythrol, EINECS 205-737-3, Erythritol, meso-, UNII-RA96B954X6, (2R,3S)-butane-1,2,3,4-tetrol (+13 more)
CAS 149-32-6
Erythritol (CAS 149-32-6) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
Erythritol
CAS Number
149-32-6
DTXSID
DTXSID6043919
Molecular Formula
C4H10O4
InChI Key
UNXHWFMMPAWVPI-ZXZARUISSA-N
Monoisotopic Mass
122.057909
Synonyms
ErythrolEINECS 205-737-3Erythritol, meso-UNII-RA96B954X6(2R,3S)-butane-1,2,3,4-tetrol1,2,3,4-ButanetetrolAntierythriteButanetetrolErythroglucinL-(-)-ThreitolL-ThreitolL-erythritol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
HumectantSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| RA96B954X6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RA96B954X6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RA96B954X6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RA96B954X6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =13100 | mg/kg bw | LD50 | oral | Rat (Male) | NTP_ICE_acute_oral |
| =13500 | mg/kg bw | LD50 | oral | Rat (Female) | NTP_ICE_acute_oral |
| >18000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =0.71 | g/kg bw/day | NOAEL | oral: drinking water | Human | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =710 | mg/kg bw/day | NOAEL | oral | Human | ToxValDB_EFSA |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Erythritol | 205-737-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
humectant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
E968
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
2 records
E968 — ADI: 500 mg/kg bw | FDA GRAS: FDA has no questions
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Erythritol?
Erythritol appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Canada; pharmaceutical. Source: EPA CPDat.
Is Erythritol used in cosmetics?
Yes, Erythritol is also indexed as a cosmetic ingredient under the name Erythritol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Erythritol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Erythritol used outside industrial chemicals?
Erythritol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.