What is the NOAEL for Gallic acid?
Gallic acid has 7 NOAEL studies in the database. The lowest reported value is 632XD903SP UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Gallic acid
Also known as: 3-10-00-02070, BRN 2050274, EINECS 205-749-9, Gallic acid, tech., Kyselina 3,4,5-trihydroxybenzoova (+4 more)
CAS 149-91-7
Gallic acid (CAS 149-91-7) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Gallic acid is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Gallic acid
CAS Number
149-91-7
DTXSID
DTXSID0020650
Molecular Formula
C7H6O5
InChI Key
LNTHITQWFMADLM-UHFFFAOYSA-N
Monoisotopic Mass
170.021523
Synonyms
3-10-00-02070BRN 2050274EINECS 205-749-9Gallic acid, tech.Kyselina 3,4,5-trihydroxybenzoovaKyselina gallovaUNII-632XD903SP3,4,5-Trihydroxy-Benzoate3,4,5-Trihydroxy-Benzoic acid
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Hazard Statements | No hazard classification according to GHS criteria |
| Short-term Effects | See Notes. |
| Long-term Effects | See Notes. |
| Routes of Exposure | The substance can be absorbed into the body by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
AntioxidantAstringentFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 632XD903SP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 632XD903SP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 632XD903SP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 632XD903SP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =119 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =119 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =119 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3,4,5-trihydroxybenzoic acid | 205-749-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GALLIC ACID
ChEMBL Phase
2
Adverse Events
0
Bioactivity
14
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Gallic acid?
Gallic acid appears on 2 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), Europe. Source: EPA CPDat.
Is Gallic acid used in cosmetics?
Yes, Gallic acid is also indexed as a cosmetic ingredient under the name Gallic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Gallic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Gallic acid have different safety status in cosmetics vs industrial chemicals?
Gallic acid is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Gallic acid used outside industrial chemicals?
Gallic acid also appears in cosmetics, pharmaceutical, food safety, cannabis databases.