What is the NOAEL for 2-Amino-5-ethylphenol hydrochloride?
2-Amino-5-ethylphenol hydrochloride has 16 NOAEL studies in the database. The lowest reported value is 7 mg/kg bw/day via oral. Source: Regulatory source.
Also known as: UNII-B5IWK1V8FX, Colorex AEP, Phenol, 2-amino-5-ethyl-, hydrochloride
CAS 149861-22-3
2-Amino-5-ethylphenol hydrochloride (CAS 149861-22-3) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 2-Amino-5-Ethylphenol HCl →
2-Amino-5-ethylphenol hydrochloride is prohibited in EU cosmetics at max 1.0% but has active industrial GHS classifications (H302, H314, H315, H317, H319, H335, H400, H410).
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7 | - | - | oral | - | Regulatory source |
| B5IWK1V8FX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.026 | mg/kg bw/d | NOAEL | oral | rat | SCCS Opinion |
| =7 | - | NOAEL | oral | - | SCCS Opinion |
| =16 | mg/kg bw/day | NOAEL | - | rat | SCCS Opinion |
| =16 | mg/kg bw/d | NOAEL | oral | rat | SCCS Opinion |
| =74 | mg/kg bw/day | NOAEL | oral | - | SCCS Opinion |
| =369 | mg/kg bw/day | NOAEL | oral | - | SCCS Opinion |
| =0.026 | mg/kg bw/d | dermal absorption | oral | rat | Regulatory source |
| =16 | mg/kg bw/d | dermal absorption | oral | rat | Regulatory source |
| 74 | mg/kg bw/day | developmental toxicity | oral | - | Regulatory source |
| 369 | mg/kg bw/day | developmental toxicity | oral | - | Regulatory source |
| 16 | mg/kg bw/day | genotoxicity | - | rat | Regulatory source |
| 16 | mg/kg bw/day | repeated dose toxicity | oral | rat | Regulatory source |
| 369 | mg/kg bw/day | repeated dose toxicity | oral | rat | Regulatory source |
| 74 | mg/kg bw/day | reproductive toxicity | oral | mouse | Regulatory source |
Showing 16 of 16 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-amino-5-ethylphenol;hydrochloride | 480-270-8 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
2-Amino-5-ethylphenol hydrochloride has 16 NOAEL studies in the database. The lowest reported value is 7 mg/kg bw/day via oral. Source: Regulatory source.
Yes, 2-Amino-5-ethylphenol hydrochloride is also indexed as a cosmetic ingredient under the name 2-Amino-5-Ethylphenol HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
2-Amino-5-ethylphenol hydrochloride is prohibited in EU cosmetics at max 1.0% but has active industrial GHS classifications (H302, H314, H315, H317, H319, H335, H400, H410).
2-Amino-5-ethylphenol hydrochloride also appears in cosmetics databases.