What is the NOAEL for Calcium stearate?
Calcium stearate has 8 NOAEL studies in the database. The lowest reported value is 32.9 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Calcium stearate
Also known as: EC No.: 216-472-8, EINECS 216-472-8, UNII-776XM7047L
CAS 1592-23-0
Calcium stearate (CAS 1592-23-0) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Calcium stearate
CAS Number
1592-23-0
DTXSID
DTXSID7027419
Molecular Formula
2C18H36O2.Ca
InChI Key
CJZGTCYPCWQAJB-UHFFFAOYSA-L
Monoisotopic Mass
608.505652
Synonyms
EC No.: 216-472-8EINECS 216-472-8UNII-776XM7047L
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | May cause mechanical irritation. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
EmulsifierAnti-caking agentViscosity modifierDyeStabilizing agentThickening agentFlame retardantBiocideSurface modifierSurfactant (surface active agent)pH regulating agentFlow promoterSoftener and conditionerWaterproofing agentProcessing aids not otherwise specifiedLubricating agentHeat stabilizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =32.9 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 776XM7047L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 776XM7047L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 776XM7047L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 776XM7047L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =2000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =2000 | mg/kg bw/day | NOAEL | dermal | Rat | ToxValDB_HPVIS |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Calcium distearate | 216-472-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CALCIUM STEARATE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Calcium stearate?
Calcium stearate appears on 5 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, active_ingredient; animal_products; Europe; pharmaceutical; residue, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 2 more. Source: EPA CPDat.
Is Calcium stearate used in cosmetics?
Yes, Calcium stearate is also indexed as a cosmetic ingredient under the name Calcium Stearate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Calcium stearate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Calcium stearate used outside industrial chemicals?
Calcium stearate also appears in cosmetics, pharmaceutical databases.