CAS 164288-56-6
1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES (CAS 164288-56-6) is a chemical substance with GHS signal word Danger; key hazard signal: H318; H400; H410. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, ECHA REACH.
View cosmetic safety profile for Cocamidopropyl Betainamide MEA Chloride →
1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES is classified GHS Danger (H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 | H318; H400; H410 | GHS05; GHS09 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Canada | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
| Personal care | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
| Substances in PCP - Canada (4/2014) | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
| Europe | - | https://mst.dk/service/publikationer/publikationsarkiv/2011/jun/survey-and-health-assessment-of-cosmetic-products-marketed-as-non-preserved/ |
| Personal care | - | https://mst.dk/service/publikationer/publikationsarkiv/2011/jun/survey-and-health-assessment-of-cosmetic-products-marketed-as-non-preserved/ |
| Europe | - | https://mst.dk/service/publikationer/publikationsarkiv/2011/jun/survey-and-health-assessment-of-cosmetic-products-marketed-as-non-preserved/ |
| Personal care | - | https://mst.dk/service/publikationer/publikationsarkiv/2011/jun/survey-and-health-assessment-of-cosmetic-products-marketed-as-non-preserved/ |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| >=1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=2420 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 2 of 2 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1-Propanaminium, 3-amino-N-[2-[(2-hydroxyethyl)amino]-2-oxoethyl]-N,N-dimethyl-, N-C12-18 acyl derivs., chlorides | 427-370-1 | ECHA overview → |
Same-CAS cosmetic ingredient record for cross-vertical context.
1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES (CAS 164288-56-6) is classified under EU CLP Annex VI as Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H318; H400; H410. Source: EU CLP Annex VI (ECHA).
1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES has 2 NOAEL studies in the database. The lowest reported value is 1000 mg/kg bw/day via oral in Rat. Source: ToxValDB_ECHA_IUCLID.
1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES appears on 4 regulatory/inventory lists including Canada, Personal care, Substances in PCP - Canada (4/2014), and 1 more. Source: EPA CPDat.
Yes, 1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES is also indexed as a cosmetic ingredient under the name Cocamidopropyl Betainamide MEA Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES is classified GHS Danger (H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
1-PROPANAMINIUM, 3-AMINO-N-[2-[(2-HYDROXYETHYL)AMINO]-2-OXOETHYL]-N,N-DIMETHYL-, N-C12-18 ACYL DERIVS., CHLORIDES also appears in cosmetics databases.