NOAEL Data REACH Registered Cosmetic Ingredient

Ethanone, 1-(2-benzofuranyl)-

Also known as: 5-17-10-00172, 2-Acetylcoumarone, 2-Acetylcumarone, Benzo(b)furan-2-yl methyl ketone, 2-Benzofuranyl methyl ketone (+6 more)

CAS 1646-26-0

Ethanone, 1-(2-benzofuranyl)- (CAS 1646-26-0) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Acetylbenzofuran →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 17 fields
Name
Ethanone, 1-(2-benzofuranyl)-
CAS Number
1646-26-0
DTXSID
DTXSID3061845
Molecular Formula
C10H8O2
InChI Key
YUTFQTAITWWGFH-UHFFFAOYSA-N
Monoisotopic Mass
160.052429
Synonyms
5-17-10-001722-Acetylcoumarone2-AcetylcumaroneBenzo(b)furan-2-yl methyl ketone2-Benzofuranyl methyl ketone1-(2-Benzofuranyl)ethanoneBRN 0117910EINECS 216-706-9NSC 23974NSC 28904UNII-A1FJQ7D0K3

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
DeodorizerFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
IFRA TransparencyIFRAIFRA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
A1FJQ7D0K3UNIIFDA UNII substance identifier--openFDA substances
A1FJQ7D0K3UNIIFDA UNII substance identifier--openFDA substances
A1FJQ7D0K3UNIIFDA UNII substance identifier--openFDA substances
A1FJQ7D0K3UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredBenzofuran-2-yl methyl ketone216-706-9ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the importation volume exceeds one tonne per annum notified chemical; b. the concentration of the notified chemical exceeds or is intended to exceed 0.10% in fine fragrances, 0.13% in face cream, 0.14% in hand cream, 0.35% in other cosmetic products or 0.05% in household cleaning products; c. information becomes available on the repeated dose toxicity of the notified chemical. 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL561390
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Ethanone, 1-(2-benzofuranyl)-?

Ethanone, 1-(2-benzofuranyl)- has 4 NOAEL studies in the database. The lowest reported value is A1FJQ7D0K3 UNII. Source: openFDA substances.

What regulatory lists include Ethanone, 1-(2-benzofuranyl)-?

Ethanone, 1-(2-benzofuranyl)- appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.

Is Ethanone, 1-(2-benzofuranyl)- used in cosmetics?

Yes, Ethanone, 1-(2-benzofuranyl)- is also indexed as a cosmetic ingredient under the name Acetylbenzofuran. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ethanone, 1-(2-benzofuranyl)- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does Ethanone, 1-(2-benzofuranyl)- have different safety status in cosmetics vs industrial chemicals?

Ethanone, 1-(2-benzofuranyl)- is prohibited in EU cosmetics but has active industrial GHS classifications (H317).

Is Ethanone, 1-(2-benzofuranyl)- used outside industrial chemicals?

Ethanone, 1-(2-benzofuranyl)- also appears in cosmetics, pharmaceutical databases.