What is the NOAEL for Josamycin?
Josamycin has 5 NOAEL studies in the database. The lowest reported value is HV13HFS217 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Josamycin
Also known as: Antibiotic yl-704 A3, EINECS 240-871-6, Josamycinum, UNII-HV13HFS217
CAS 16846-24-5
Josamycin (CAS 16846-24-5) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Josamycin
CAS Number
16846-24-5
DTXSID
DTXSID8023183
Molecular Formula
C42H69NO15
InChI Key
XJSFLOJWULLJQS-HTYUZQQASA-N
Monoisotopic Mass
827.466721
Synonyms
Antibiotic yl-704 A3EINECS 240-871-6JosamycinumUNII-HV13HFS217
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| HV13HFS217 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HV13HFS217 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HV13HFS217 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HV13HFS217 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >7000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
JOSAMYCIN
ChEMBL Phase
3
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include Josamycin?
Josamycin appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Josamycin used in cosmetics?
Yes, Josamycin is also indexed as a cosmetic ingredient under the name Ammonium Methacrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Josamycin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Josamycin used outside industrial chemicals?
Josamycin also appears in cosmetics, pharmaceutical databases.