What is the NOAEL for Ammonium hexafluorosilicate?
Ammonium hexafluorosilicate has 6 NOAEL studies in the database. The lowest reported value is 1X545W620G UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ammonium hexafluorosilicate
Also known as: AI3-25550-X, Caswell No. 043, Diammonium fluorosilicate, EINECS 240-968-3, EPA Pesticide Chemical Code 075301 (+3 more)
CAS 16919-19-0
Ammonium hexafluorosilicate (CAS 16919-19-0) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Ammonium hexafluorosilicate is classified GHS Danger (H301, H311, H331, H412) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Ammonium hexafluorosilicate
CAS Number
16919-19-0
DTXSID
DTXSID6047076
Molecular Formula
F6Si.2H3N
InChI Key
ITHIMUMYFVCXSL-UHFFFAOYSA-P
Monoisotopic Mass
176.020444
Synonyms
AI3-25550-XCaswell No. 043Diammonium fluorosilicateEINECS 240-968-3EPA Pesticide Chemical Code 075301Fluorosilicic acid, ammonium saltSilicate, hexafluoro-, diammoniumUNII-1X545W620G
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Pharmaceutical
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care; restricted | European Commission | CosIng |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1X545W620G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1X545W620G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1X545W620G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1X545W620G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ~8 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~9.6 | mg/m3 | LEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ammonium hexafluorosilicate | 240-968-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
0.15%
Category
Cosmetic Ingredient
Frequently Asked Questions
What regulatory lists include Ammonium hexafluorosilicate?
Ammonium hexafluorosilicate appears on 4 regulatory/inventory lists including Europe; Personal care; restricted, inert_ingredient; non_food_use; Pesticides, CEDI, and 1 more. Source: EPA CPDat.
Is Ammonium hexafluorosilicate used in cosmetics?
Yes, Ammonium hexafluorosilicate is also indexed as a cosmetic ingredient under the name Ammonium Fluorosilicate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ammonium hexafluorosilicate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Ammonium hexafluorosilicate have different safety status in cosmetics vs industrial chemicals?
Ammonium hexafluorosilicate is classified GHS Danger (H301, H311, H331, H412) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
Is Ammonium hexafluorosilicate used outside industrial chemicals?
Ammonium hexafluorosilicate also appears in cosmetics databases.