NOAEL Data REACH Registered Cosmetic Ingredient

Gamma-Cyclodextrin

Also known as: gamma-Dextrin, Dexy Pearl gamma-100, EINECS 241-482-4, UNII-KZJ0BYZ5VA, Gamma cyclodextrin (+1 more)

CAS 17465-86-0

Gamma-Cyclodextrin (CAS 17465-86-0) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Gamma-Cyclodextrin →

SOURCE noael studies public
NOAEL studies
9
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Gamma-Cyclodextrin
CAS Number
17465-86-0
DTXSID
DTXSID5047033
Molecular Formula
C48H80O40
InChI Key
GDSRMADSINPKSL-HSEONFRVSA-N
Monoisotopic Mass
1296.422587
Synonyms
gamma-DextrinDexy Pearl gamma-100EINECS 241-482-4UNII-KZJ0BYZ5VAGamma cyclodextringamma-CD

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 9 of 9 studies
ValueUnitEndpointRouteSpeciesSource
KZJ0BYZ5VAUNIIFDA UNII substance identifier--openFDA substances
KZJ0BYZ5VAUNIIFDA UNII substance identifier--openFDA substances
KZJ0BYZ5VAUNIIFDA UNII substance identifier--openFDA substances
KZJ0BYZ5VAUNIIFDA UNII substance identifier--openFDA substances
>3750mg/kg bw/dayLELinjectionRatToxValDB_ECHA_IUCLID
>4600mg/kg bw/dayLELinjectionRatToxValDB_ECHA_IUCLID
=10000mg/kg bw/dayLELinjectionMouseToxValDB_ECHA_IUCLID
-unitlessModel Score--NTP_ICE_endocrine
=120mg/kg bw/dayNOAELinjectionRatToxValDB_ECHA_IUCLID

Showing 9 of 9 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredCyclooctapentylose241-482-4ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Polysaccharides
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL GAMMA-CYCLODEXTRIN
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
1
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

FDA GRAS: FDA has no questions

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for Gamma-Cyclodextrin?

Gamma-Cyclodextrin has 9 NOAEL studies in the database. The lowest reported value is KZJ0BYZ5VA UNII. Source: openFDA substances.

What regulatory lists include Gamma-Cyclodextrin?

Gamma-Cyclodextrin appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is Gamma-Cyclodextrin used in cosmetics?

Yes, Gamma-Cyclodextrin is also indexed as a cosmetic ingredient under the name Gamma-Cyclodextrin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Gamma-Cyclodextrin come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is Gamma-Cyclodextrin used outside industrial chemicals?

Gamma-Cyclodextrin also appears in cosmetics, pharmaceutical, food safety databases.