What is the NOAEL for Allyl phenylacetate?
Allyl phenylacetate has 19 NOAEL studies in the database. The lowest reported value is 0.48 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
Allyl phenylacetate
Also known as: Benzeneacetic acid, 2-propenyl ester, Benzeneacetic acid, 2-propen-1-yl ester, 3-09-00-02181, Allyl alpha-toluate, BRN 1867491 (+7 more)
CAS 1797-74-6
Allyl phenylacetate (CAS 1797-74-6) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Allyl phenylacetate is classified GHS Danger (H301, H311, H302, H315, H317, H319) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
19
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Allyl phenylacetate
CAS Number
1797-74-6
DTXSID
DTXSID8061977
Molecular Formula
C11H12O2
InChI Key
ZCDYAMJXVAUTIM-UHFFFAOYSA-N
Monoisotopic Mass
176.08373
Synonyms
Benzeneacetic acid, 2-propenyl esterBenzeneacetic acid, 2-propen-1-yl ester3-09-00-02181Allyl alpha-toluateBRN 1867491EINECS 217-281-2FEMA No. 2039NSC 6574Phenylacetic acid allyl ester2-Propenyl benzeneacetate2-Propenyl phenylacetateUNII-3D2NBC7K7Q
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 19 of 19 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0.6 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1.25 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 0.48 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 1 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 3D2NBC7K7Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3D2NBC7K7Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3D2NBC7K7Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3D2NBC7K7Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 48 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 100 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2025 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 8100 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 405 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 843.75 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 324 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 675 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| =650 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 19 of 19 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Allyl phenylacetate?
Allyl phenylacetate appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Allyl phenylacetate used in cosmetics?
Yes, Allyl phenylacetate is also indexed as a cosmetic ingredient under the name Allyl Phenylacetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Allyl phenylacetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Allyl phenylacetate have different safety status in cosmetics vs industrial chemicals?
Allyl phenylacetate is classified GHS Danger (H301, H311, H302, H315, H317, H319) in the chemicals database but is restricted in EU cosmetics.
Is Allyl phenylacetate used outside industrial chemicals?
Allyl phenylacetate also appears in cosmetics, cannabis databases.