What is the NOAEL for C.I. Acid Orange 10?
C.I. Acid Orange 10 has 11 NOAEL studies in the database. The lowest reported value is 1Q6EJU80RN UNII. Source: openFDA substances.
NOAEL Data
IARC Group 3
Cosmetic Ingredient
C.I. Acid Orange 10
Also known as: Orange G, 1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-(2-phenyldiazenyl)-, sodium salt (1:2), D and C Orange No. 3, 1370 Orange, D&C Orange No. 3 (+15 more)
CAS 1936-15-8
C.I. Acid Orange 10 (CAS 1936-15-8) is a chemical substance; key hazard signal: IARC Group 3. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, IARC.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
C.I. Acid Orange 10
CAS Number
1936-15-8
DTXSID
DTXSID6021082
Molecular Formula
C16H12N2O7S2.2Na
InChI Key
HSXUHWZMNJHFRV-UHFFFAOYSA-L
Monoisotopic Mass
453.988132
Synonyms
Orange G1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-(2-phenyldiazenyl)-, sodium salt (1:2)D and C Orange No. 31370 OrangeD&C Orange No. 3Acid Fast Orange GAcid Fast Orange EGGAcid Leather Orange KGAcid Leather Orange PGWAcid Light Orange GAcid Light Orange JAcid Light Orange JA Export
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1987 | 8, Sup 7 |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1Q6EJU80RN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1Q6EJU80RN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1Q6EJU80RN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1Q6EJU80RN | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 3000 | ppm | Top dose | Dosed feed | Rat | NTP_ICE_cancer |
| 6000 | ppm | Top dose | Dosed feed | Mouse | NTP_ICE_cancer |
Showing 11 of 11 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ORANGE G SODIUM
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include C.I. Acid Orange 10?
C.I. Acid Orange 10 appears on 1 regulatory/inventory list including Europe; Personal care. Source: EPA CPDat.
Is C.I. Acid Orange 10 a carcinogen according to IARC?
C.I. Acid Orange 10 is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1987). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Is C.I. Acid Orange 10 used in cosmetics?
Yes, C.I. Acid Orange 10 is also indexed as a cosmetic ingredient under the name CI 16230. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Acid Orange 10 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is C.I. Acid Orange 10 used outside industrial chemicals?
C.I. Acid Orange 10 also appears in cosmetics, pharmaceutical databases.