NOAEL Data Cosmetic Ingredient

1,4-Tetrahydrothiazine-3-one

Also known as: 4-27-00-02550, BRN 0107799, EINECS 243-581-8, NSC 27540, 3-Oxothiomorpholine (+1 more)

CAS 20196-21-8

1,4-Tetrahydrothiazine-3-one (CAS 20196-21-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Thiomorpholinone →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
1,4-Tetrahydrothiazine-3-one
CAS Number
20196-21-8
DTXSID
DTXSID00174033
Molecular Formula
C4H7NOS
InChI Key
HBDDRESWUAFAHY-UHFFFAOYSA-N
Monoisotopic Mass
117.024835
Synonyms
4-27-00-02550BRN 0107799EINECS 243-581-8NSC 275403-OxothiomorpholineUNII-SK56OUS8CH

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
AntioxidantSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
SK56OUS8CHUNIIFDA UNII substance identifier--openFDA substances
SK56OUS8CHUNIIFDA UNII substance identifier--openFDA substances
SK56OUS8CHUNIIFDA UNII substance identifier--openFDA substances
SK56OUS8CHUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 1,4-Tetrahydrothiazine-3-one?

1,4-Tetrahydrothiazine-3-one has 4 NOAEL studies in the database. The lowest reported value is SK56OUS8CH UNII. Source: openFDA substances.

Is 1,4-Tetrahydrothiazine-3-one used in cosmetics?

Yes, 1,4-Tetrahydrothiazine-3-one is also indexed as a cosmetic ingredient under the name Thiomorpholinone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 1,4-Tetrahydrothiazine-3-one come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 1,4-Tetrahydrothiazine-3-one used outside industrial chemicals?

1,4-Tetrahydrothiazine-3-one also appears in cosmetics databases.