What is the NOAEL for Zinc hydroxide?
Zinc hydroxide has 14 NOAEL studies in the database. The lowest reported value is OXK3V8KJ7L UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Zinc hydroxide
Also known as: Zinc hydroxide (Zn(OH)2), Caswell No. 916, EINECS 243-814-3, EPA Pesticide Chemical Code 088501
CAS 20427-58-1
Zinc hydroxide (CAS 20427-58-1) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
14
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Zinc hydroxide
CAS Number
20427-58-1
DTXSID
DTXSID7042516
Molecular Formula
2H2O.Zn
InChI Key
UGZADUVQMDAIAO-UHFFFAOYSA-L
Monoisotopic Mass
99.950271
Synonyms
Zinc hydroxide (Zn(OH)2)Caswell No. 916EINECS 243-814-3EPA Pesticide Chemical Code 088501
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
AbsorbentProcessing aids not otherwise specifiedNo specific technical functionAntioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 14 of 14 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| OXK3V8KJ7L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OXK3V8KJ7L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OXK3V8KJ7L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OXK3V8KJ7L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1 | mg/m3 | LEL | inhalation | Guinea Pig | ToxValDB_ECHA_IUCLID |
| =2.5 | mg/m3 | LEL | inhalation | Guinea Pig | ToxValDB_ECHA_IUCLID |
| =5 | mg/m3 | LEL | inhalation | Rabbit | ToxValDB_ECHA_IUCLID |
| =0.55 | mg/m3 | LOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =4.45 | mg/m3 | LOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =7.5 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =0.47 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =1.48 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =1.96 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =15 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 14 of 14 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Zinc hydroxide | 243-814-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Frequently Asked Questions
What regulatory lists include Zinc hydroxide?
Zinc hydroxide appears on 2 regulatory/inventory lists including Indirect additives food contact (10/2018), inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Zinc hydroxide used in cosmetics?
Yes, Zinc hydroxide is also indexed as a cosmetic ingredient under the name ZINC HYDROXIDE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Zinc hydroxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Zinc hydroxide used outside industrial chemicals?
Zinc hydroxide also appears in cosmetics databases.