CAS 207562-42-3
Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane (CAS 207562-42-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, SCCS.
View cosmetic safety profile for Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane →
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1 | % | - | oral | human | Regulatory source |
| 1.34 | mg/kg bw/day | - | oral | rat | Regulatory source |
| 3.3 | - | - | oral | human | Regulatory source |
| =4.46 | % | - | oral | human | Regulatory source |
| 8 | - | - | oral | human | Regulatory source |
| 10 | - | - | oral | - | Regulatory source |
| 10 | % | - | oral | - | Regulatory source |
| 100 | % | - | oral | rat | Regulatory source |
| 1000 | mg/kg bw/d | - | oral | - | Regulatory source |
| =1000 | mg/kg bw/d | - | oral | rat | Regulatory source |
| 50I65NU3DV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1 | % | NOAEL | oral | human | SCCS Opinion |
| =1.34 | mg/kg bw/day | NOAEL | oral | rat | SCCS Opinion |
| =3.3 | - | NOAEL | oral | human | SCCS Opinion |
| =4.46 | % | NOAEL | oral | human | SCCS Opinion |
| =8 | - | NOAEL | oral | human | SCCS Opinion |
| =10 | - | NOAEL | oral | - | SCCS Opinion |
| =100 | % | NOAEL | oral | rat | SCCS Opinion |
| =1000 | mg/kg bw/day | NOAEL | oral | rat | SCCS Opinion |
| =1000 | mg/kg bw/d | NOAEL | oral | - | SCCS Opinion |
| 1000 | mg/kg bw/day | developmental toxicity | - | - | Regulatory source |
| 1000 | mg/kg bw/d | genotoxicity | oral | - | Regulatory source |
| 1000 | mg/kg bw/d | genotoxicity | oral | mouse | Regulatory source |
| 1000 | mg/kg bw/day | repeated dose toxicity | oral | rat | Regulatory source |
| 1000 | mg/kg bw/d | reproductive toxicity | oral | - | Regulatory source |
Showing 25 of 25 studies
EU Scientific Committee opinions tied to the matched substance.
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCS/1425/11 | 22 March 2011 | insufficient data | None established (cannot be assessed) | Insufficient dermal toxicity data; low oral bioavailability indicated; secondary amine prone to nitrosation; no inhalation data; 90-day dermal toxicity study required |
| SCCS/1335/10 | 2011-03-22 | The SCCS considers that the safe use of Bis(butylbenzoate) diaminotriazine aminopropyltrisiloxane as an UV-filter in cosmetic products in a concentration up to maximum 10.0% cannot be assessed based on the available data. As low oral bioavailability of the substance is anticipated, a quantitative risk assessment based on the oral NOAEL cannot be performed in the absence of adequate information on the extent of internal exposure. | 10.0% | Safe use cannot be assessed; very low oral bioavailability prevents oral-NOAEL-based MoS calculation; additional data (e.g. 90-day dermal toxicity study or sound oral bioavailability data) required, though such studies are no longer permitted in the EU. |
Same-CAS cosmetic ingredient record for cross-vertical context.
Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane has 25 NOAEL studies in the database. The lowest reported value is 1 % via oral in human. Source: Regulatory source.
Yes, Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane is also indexed as a cosmetic ingredient under the name Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane also appears in cosmetics databases.