What is the NOAEL for Trolamine salicylate?
Trolamine salicylate has 4 NOAEL studies in the database. The lowest reported value is H8O4040BHD UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Trolamine salicylate
Also known as: Benzoic acid, 2-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:1), EINECS 218-531-3, Arthricream
CAS 2174-16-5
Trolamine salicylate (CAS 2174-16-5) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Trolamine salicylate
CAS Number
2174-16-5
DTXSID
DTXSID4047969
Molecular Formula
C7H6O3.C6H15NO3
InChI Key
UEVAMYPIMMOEFW-UHFFFAOYSA-N
Monoisotopic Mass
287.136887
Synonyms
Benzoic acid, 2-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:1)EINECS 218-531-3Arthricream
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
PreservativeUV stabilizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| H8O4040BHD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H8O4040BHD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H8O4040BHD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H8O4040BHD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
0.5%
Category
UV Filter
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TROLAMINE SALICYLATE
ChEMBL Phase
-1
Adverse Events
81
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Trolamine salicylate?
Trolamine salicylate appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Canada; pharmaceutical. Source: EPA CPDat.
Is Trolamine salicylate used in cosmetics?
Yes, Trolamine salicylate is also indexed as a cosmetic ingredient under the name TEA-Salicylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Trolamine salicylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Trolamine salicylate used outside industrial chemicals?
Trolamine salicylate also appears in cosmetics, pharmaceutical databases.