NOAEL Data Cosmetic Ingredient

Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?)

CAS 22036-78-8

Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) (CAS 22036-78-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Disodium Hydroxyethylamino Bismethylphosphonate →

SOURCE noael studies public
NOAEL studies
2
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 3 fields
Name
Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?)
CAS Number
22036-78-8
DTXSID
DTXSID901089735

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Chelating agent

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 2 of 2 studies
ValueUnitEndpointRouteSpeciesSource
>=1000mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>=1000mg/kg bw/dayNOELoralRatToxValDB_ECHA_IUCLID

Showing 2 of 2 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. If the assessment report about the chemical recommends secondary notification of the chemical in particular circumstances and any of the circumstances occur in relation to the introduction (importation or manufacture) of the chemical by a person, then the person introducing this chemical must tell us in writing within 28 calendar days that the circumstances have occurred. 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?)?

Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) has 2 NOAEL studies in the database. The lowest reported value is 1000 mg/kg bw/day via oral in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) used in cosmetics?

Yes, Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) is also indexed as a cosmetic ingredient under the name Disodium Hydroxyethylamino Bismethylphosphonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) have different safety status in cosmetics vs industrial chemicals?

Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) is classified GHS Danger (H290, H302, H314, H318, H319, H332, H412) in the chemicals database but is allowed in EU cosmetics.

Is Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) used outside industrial chemicals?

Phosphonic acid, P,P′-[[(2-hydroxyethyl)imino]bis(methylene)]bis-, sodium salt (1:?) also appears in cosmetics databases.