NOAEL Data Cosmetic Ingredient

Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)-

CAS 22037-88-3

Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)- (CAS 22037-88-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for OCTAHYDRO-TRIMETHYLSPIRO-METHANOAZULENE-6,2'-OXIRANE →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)-
CAS Number
22037-88-3
DTXSID
DTXSID80885190
Molecular Formula
C15H24O
InChI Key
BWDPPCMUUFETAC-MIBAYGRRSA-N
Monoisotopic Mass
220.182715

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Fragrance

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
G4HFM2Q6LLUNIIFDA UNII substance identifier--openFDA substances
G4HFM2Q6LLUNIIFDA UNII substance identifier--openFDA substances
G4HFM2Q6LLUNIIFDA UNII substance identifier--openFDA substances
G4HFM2Q6LLUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)-?

Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)- has 4 NOAEL studies in the database. The lowest reported value is G4HFM2Q6LL UNII. Source: openFDA substances.

Is Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)- used in cosmetics?

Yes, Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)- is also indexed as a cosmetic ingredient under the name OCTAHYDRO-TRIMETHYLSPIRO-METHANOAZULENE-6,2'-OXIRANE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)- used outside industrial chemicals?

Spiro[6H-3a,7-methanoazulene-6,2'-oxirane], octahydro-3,8,8-trimethyl-, (2'R,3R,3aS,7R,8aS)- also appears in cosmetics databases.