What is the NOAEL for N-Isopropylacrylamide?
N-Isopropylacrylamide has 5 NOAEL studies in the database. The lowest reported value is B7GFF17L9U UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N-Isopropylacrylamide
Also known as: 4-04-00-00517, BRN 1744926, EINECS 218-638-5, Isopropyl acrylamide, Isopropylamid kyseliny akrylove (+1 more)
CAS 2210-25-5
N-Isopropylacrylamide (CAS 2210-25-5) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
View cosmetic safety profile for Isopropylacrylamide (N-Isopropylacrylamide) →
Cross-Vertical Regulatory Divergence
N-Isopropylacrylamide is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H318, H319, H312, H373).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
N-Isopropylacrylamide
CAS Number
2210-25-5
DTXSID
DTXSID0033754
Molecular Formula
C6H11NO
InChI Key
QNILTEGFHQSKFF-UHFFFAOYSA-N
Monoisotopic Mass
113.084064
Synonyms
4-04-00-00517BRN 1744926EINECS 218-638-5Isopropyl acrylamideIsopropylamid kyseliny akryloveUNII-B7GFF17L9U
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
No specific technical function
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| B7GFF17L9U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B7GFF17L9U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B7GFF17L9U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B7GFF17L9U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =375 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | N-isopropylacrylamide | 218-638-5 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1527236
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
Is N-Isopropylacrylamide used in cosmetics?
Yes, N-Isopropylacrylamide is also indexed as a cosmetic ingredient under the name Isopropylacrylamide (N-Isopropylacrylamide). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-Isopropylacrylamide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does N-Isopropylacrylamide have different safety status in cosmetics vs industrial chemicals?
N-Isopropylacrylamide is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H318, H319, H312, H373).
Is N-Isopropylacrylamide used outside industrial chemicals?
N-Isopropylacrylamide also appears in cosmetics, pharmaceutical databases.