What is the NOAEL for Ambroxolhydrochloride?
Ambroxolhydrochloride has 5 NOAEL studies in the database. The lowest reported value is CC995ZMV90 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Ambroxolhydrochloride
Also known as: Ambroxol hydrochloride, trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, EINECS 245-899-2, Mucolear, Mucosolvan (+4 more)
CAS 23828-92-4
Ambroxolhydrochloride (CAS 23828-92-4) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Tetrahydroxypropyl Ethylenediamine Dioleate →
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Ambroxolhydrochloride
CAS Number
23828-92-4
DTXSID
DTXSID2045442
Molecular Formula
C13H18Br2N2O.ClH
InChI Key
QNVKOSLOVOTXKF-PFWPSKEQSA-N
Monoisotopic Mass
411.955266
Synonyms
Ambroxol hydrochloridetrans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochlorideEINECS 245-899-2MucolearMucosolvanNA 872 hydrochlorideMucoanginAmbroxol lozengeUNII-CC995ZMV90
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| CC995ZMV90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CC995ZMV90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CC995ZMV90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| CC995ZMV90 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =4203 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1514634
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include Ambroxolhydrochloride?
Ambroxolhydrochloride appears on 1 regulatory/inventory list including active_ingredient; Australia. Source: EPA CPDat.
Is Ambroxolhydrochloride used in cosmetics?
Yes, Ambroxolhydrochloride is also indexed as a cosmetic ingredient under the name Tetrahydroxypropyl Ethylenediamine Dioleate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ambroxolhydrochloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Ambroxolhydrochloride used outside industrial chemicals?
Ambroxolhydrochloride also appears in cosmetics, pharmaceutical databases.