What is the NOAEL for Auramine hydrochloride?
Auramine hydrochloride has 10 NOAEL studies in the database. The lowest reported value is 7.187112622 uM. Source: NTP_ICE_endocrine.
NOAEL Data
Cosmetic Ingredient
Auramine hydrochloride
Also known as: Benzophenoneidum, C.I. Basic Yellow No. 2, Auramine-O, Aizen Auramine Conc. SFA, Aniline, 4,4'-imidocarbonylbis(N,N-dimethyl-, monohydrochloride (+15 more)
CAS 2465-27-2
Auramine hydrochloride (CAS 2465-27-2) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for CI 41000 (Auramine O / Basic Yellow 2) →
Cross-Vertical Regulatory Divergence
Auramine hydrochloride is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H311, H319, H351, H373, H400, H410, H411).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Auramine hydrochloride
CAS Number
2465-27-2
DTXSID
DTXSID9020114
Molecular Formula
C17H21N3.ClH
InChI Key
KSCQDDRPFHTIRL-UHFFFAOYSA-N
Monoisotopic Mass
303.150225
Synonyms
BenzophenoneidumC.I. Basic Yellow No. 2Auramine-OAizen Auramine Conc. SFAAniline, 4,4'-imidocarbonylbis(N,N-dimethyl-, monohydrochlorideAuramine O Extra Conc. A ExportAuramine ExtraAuramine Extra Conc. ABasic Yellow 2, fugitive4,4'-Bis(dimethylamino)-benzhydrylidenimine hydrochlorideCI Basic Yellow 2CI Basic Yellow 2, monohydrochloride
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7.762592869 | uM | AC50 | - | - | NTP_ICE_endocrine |
| 7.187112622 | uM | ACC | - | - | NTP_ICE_endocrine |
| 8.66 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| DL992L7W39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DL992L7W39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DL992L7W39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DL992L7W39 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.107 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 0.0904 | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 10 of 10 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorants
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1612246
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include Auramine hydrochloride?
Auramine hydrochloride appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Auramine hydrochloride used in cosmetics?
Yes, Auramine hydrochloride is also indexed as a cosmetic ingredient under the name CI 41000 (Auramine O / Basic Yellow 2). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Auramine hydrochloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Auramine hydrochloride have different safety status in cosmetics vs industrial chemicals?
Auramine hydrochloride is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H311, H319, H351, H373, H400, H410, H411).
Is Auramine hydrochloride used outside industrial chemicals?
Auramine hydrochloride also appears in cosmetics, pharmaceutical databases.