NOAEL Data Cosmetic Ingredient

2-Pentylidenecyclohexan-1-one

CAS 25677-40-1

2-Pentylidenecyclohexan-1-one (CAS 25677-40-1) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for 2-Heptylidenecyclopentanone →

SOURCE noael studies public
NOAEL studies
11
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
2-Pentylidenecyclohexan-1-one
CAS Number
25677-40-1
DTXSID
DTXSID70865244
Molecular Formula
C11H18O
InChI Key
KTETXLGRNPACFS-UHFFFAOYSA-N
Monoisotopic Mass
166.135765

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
banned; Europe; Personal careEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 11 of 11 studies
ValueUnitEndpointRouteSpeciesSource
0.5952%Concentration, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
0.4762%Concentration, one positive responseDermalHumanNTP_ICE_skin_sensitization
YB5LR0BA4FUNIIFDA UNII substance identifier--openFDA substances
YB5LR0BA4FUNIIFDA UNII substance identifier--openFDA substances
YB5LR0BA4FUNIIFDA UNII substance identifier--openFDA substances
YB5LR0BA4FUNIIFDA UNII substance identifier--openFDA substances
84%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
6750ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
401.8ug/cm2Induction dose per skin area, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
321.4ug/cm2Induction dose per skin area, one positive responseDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 11 of 11 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 2-Pentylidenecyclohexan-1-one?

2-Pentylidenecyclohexan-1-one has 11 NOAEL studies in the database. The lowest reported value is 0.4762 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.

What regulatory lists include 2-Pentylidenecyclohexan-1-one?

2-Pentylidenecyclohexan-1-one appears on 1 regulatory/inventory list including banned; Europe; Personal care. Source: EPA CPDat.

Is 2-Pentylidenecyclohexan-1-one used in cosmetics?

Yes, 2-Pentylidenecyclohexan-1-one is also indexed as a cosmetic ingredient under the name 2-Heptylidenecyclopentanone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-Pentylidenecyclohexan-1-one come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 2-Pentylidenecyclohexan-1-one used outside industrial chemicals?

2-Pentylidenecyclohexan-1-one also appears in cosmetics databases.